Ideas

Lifespan extension therapy: Amorfrutin A, isolated from Amorpha fruticosa L,  may increase life span via up-regulation of its target gene BubR1, 8/October/2017, 10.45 pm
Lifespan extension therapy: Amorfrutin A, isolated from Amorpha fruticosa L,  may increase life span via up-regulation of its target gene BubR1, 8/October/2017, 10.45 pm 960 720 Dr Boomi's Genom-2-Discovery Center

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and Department of Pharmacology, School…

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Natural product therapy for Non-alcoholic fatty liver disease (NAFLD): Hesperidin, isolated from Citrus fruits, promotes degradation of HMGCR, decreases the levels of triglycerides, free cholesterol, and total cholesterol and prevents the progression of Non-alcoholic fatty liver disease (NAFLD via down regulation of its target gene, 8/November/2017, 10.37 pm
Natural product therapy for Non-alcoholic fatty liver disease (NAFLD): Hesperidin, isolated from Citrus fruits, promotes degradation of HMGCR, decreases the levels of triglycerides, free cholesterol, and total cholesterol and prevents the progression of Non-alcoholic fatty liver disease (NAFLD via down regulation of its target gene, 8/November/2017, 10.37 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Significance of the study: Given that: (1)  15-30% of Western populations suffer from Non-alcoholic fatty liver disease (NAFLD), while 6-25% of Asian populations suffer from it; (2) 75 to 100 million people in…

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Molecular therapy for Stroke: A therapeutic mix encompassing docosahexaenoic acid (DHA) and aspirin (ASA) [DHAASA] attenuates hippocampal neurons injury, augments regenerative neurogenesis after Ischemic Stroke, and ameliorates stroke damage and neurological deficits via up regulation of its target genes BDNF and NAMPT, 7/November/2017, 11.43 pm
Molecular therapy for Stroke: A therapeutic mix encompassing docosahexaenoic acid (DHA) and aspirin (ASA) [DHAASA] attenuates hippocampal neurons injury, augments regenerative neurogenesis after Ischemic Stroke, and ameliorates stroke damage and neurological deficits via up regulation of its target genes BDNF and NAMPT, 7/November/2017, 11.43 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A recent study from Research Center for Neurobiology and Department of Neurobiology, Xuzhou Medical College, 209 Tongshan Road, Xuzhou, Jiangsu 221004, PR China; and School of Public…

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Molecular therapy for heart regeneration and repair: A therapeutic mix encompassing Atorvastatin and Probucol increases Agrin expression, activates Yap and ERK-mediated signaling,  replaces scar tissue with functional cardiomyocytes, and promotes cardiomyocyte regeneration and repair after myocardial infarction, via up regulation of its target gene, 7/November/2017, 11.07 pm
Molecular therapy for heart regeneration and repair: A therapeutic mix encompassing Atorvastatin and Probucol increases Agrin expression, activates Yap and ERK-mediated signaling,  replaces scar tissue with functional cardiomyocytes, and promotes cardiomyocyte regeneration and repair after myocardial infarction, via up regulation of its target gene, 7/November/2017, 11.07 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A recent study from Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel; Department of Biomedical Engineering, Duke University, Durham, North Carolina 27708,…

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Antiviral therapy for chikungunya (CHIKV) and Zika (ZIKV) viruses: Nafamostat Mesilate increases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication via up regulation of its target gene, 7/November/2017, 10.53 pm
Antiviral therapy for chikungunya (CHIKV) and Zika (ZIKV) viruses: Nafamostat Mesilate increases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication via up regulation of its target gene, 7/November/2017, 10.53 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Viral Populations and Pathogenesis Unit, Institut Pasteur, CNRS UMR 3569, 25–28 rue du Dr. Roux, 75724 Paris Cedex 15, France shows that…

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Lifespan extension therapy: 5,4′-dihydroxy-7,8-dimethoxyflavanone (DHDMF), found abundantly in Dodonaea viscosa,  may increase life span via up-regulation of its target gene BubR1, 7/November/2017, 9.17 am
Lifespan extension therapy: 5,4′-dihydroxy-7,8-dimethoxyflavanone (DHDMF), found abundantly in Dodonaea viscosa,  may increase life span via up-regulation of its target gene BubR1, 7/November/2017, 9.17 am 960 720 Dr Boomi's Genom-2-Discovery Center

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and Department of Pharmacology, School…

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