Ideas

Hunger hormone-based therapy for lowering cholesterol, and triglycerides levels: Ghrelin, a digestive hormone that controls appetite, decreases the levels of HMGCR,  triglycerides, free cholesterol, and total cholesterol and prevents the progression of Non-alcoholic fatty liver disease (NAFLD), via up-regulation of its target gene, 27/April/2019, 11.57 pm
Hunger hormone-based therapy for lowering cholesterol, and triglycerides levels: Ghrelin, a digestive hormone that controls appetite, decreases the levels of HMGCR,  triglycerides, free cholesterol, and total cholesterol and prevents the progression of Non-alcoholic fatty liver disease (NAFLD), via up-regulation of its target gene, 27/April/2019, 11.57 pm 960 720 Dr Boomi's Genom-2-Discovery Center

The significance of the study: Given that: (1)  15-30% of Western populations suffer from Non-alcoholic fatty liver disease (NAFLD), while 6-25% of Asian populations suffer from it; (2) 75 to 100 million people…

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PIM-1-based Regenerative therapy for regaining the lost cardiomyocytes in Myocardial patients: PIM-1, a regulator of cell cycle progression, increases the expression of ERBB2/Her2 and promotes dedifferentiation  of cardiomyocytes, via up-regulation of its target gene, 27/April/2019, 11.40 pm
PIM-1-based Regenerative therapy for regaining the lost cardiomyocytes in Myocardial patients: PIM-1, a regulator of cell cycle progression, increases the expression of ERBB2/Her2 and promotes dedifferentiation  of cardiomyocytes, via up-regulation of its target gene, 27/April/2019, 11.40 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A recent study from the Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel shows that “ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation.” This study was published, in the 6 April…

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Natural product-based therapy for anxiety and depression: Tanshinone IIA, derived from Salvia miltiorrhiza,  decreases PHF8 levels, increases the expression of serotonin receptors Htr1a and Htr2a, and promotes resistance to stress-induced -anxiety and -depression, via down-regulation of its target gene, 27/April/2019, 11.12 pm
Natural product-based therapy for anxiety and depression: Tanshinone IIA, derived from Salvia miltiorrhiza,  decreases PHF8 levels, increases the expression of serotonin receptors Htr1a and Htr2a, and promotes resistance to stress-induced -anxiety and -depression, via down-regulation of its target gene, 27/April/2019, 11.12 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say:  A study from Department of Molecular Biology, Cancer Center and Center for Regenerative Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA; Department of Stem Cell and…

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Erythropoietin/Haematopoietin-derived peptide protects against cardiomyopathy: Intracardiac/Epicardial injection of Cyclin helix B peptide (CHBP) protects against Cardiomyopathy: Cyclin helix B peptide (CHBP) decreases the expression of Sox6, restores the balance between slow- and fast-twitch myofiber proteins and alleviates Cardiomyopathy, via upregulation of its target gene, 27/April/2019, 10.45 pm
Erythropoietin/Haematopoietin-derived peptide protects against cardiomyopathy: Intracardiac/Epicardial injection of Cyclin helix B peptide (CHBP) protects against Cardiomyopathy: Cyclin helix B peptide (CHBP) decreases the expression of Sox6, restores the balance between slow- and fast-twitch myofiber proteins and alleviates Cardiomyopathy, via upregulation of its target gene, 27/April/2019, 10.45 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A recent study from the Department of Cardiology, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, USA; and Harvard Stem Cell Institute, Harvard University, Cambridge, Massachusetts, USA shows that “Trbp regulates heart function through microRNA-mediated Sox6 repression.” This…

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Ghrelin-based therapy for body weight control, energy homeostasis and TIIDM: Ghrelin  decreases CADM1 and its downstream target genes that inhibit glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM, via up-regulation of its target gene, 27/April/2019, 3.57pm
Ghrelin-based therapy for body weight control, energy homeostasis and TIIDM: Ghrelin  decreases CADM1 and its downstream target genes that inhibit glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM, via up-regulation of its target gene, 27/April/2019, 3.57pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say  A study from the Max Delbrück Center for Molecular Medicine, Berlin, Germany shows that “Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule1.”…

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Molecular therapy for body weight control, energy homeostasis and TIIDM: Piromelatine,  a melatonin receptor agonist, inhibits DNA methyltransferase 3a (Dnmt3a) expression, increases FGF21 expression, augments insulin sensitivity, increases glucose tolerance, and protects from diet-induced obesity and TIIDM, via up-regulation of its target gene, 26/April/2019, 11.19 pm
Molecular therapy for body weight control, energy homeostasis and TIIDM: Piromelatine,  a melatonin receptor agonist, inhibits DNA methyltransferase 3a (Dnmt3a) expression, increases FGF21 expression, augments insulin sensitivity, increases glucose tolerance, and protects from diet-induced obesity and TIIDM, via up-regulation of its target gene, 26/April/2019, 11.19 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say  A study from Nutritional Sciences and Toxicology Department, University of California, Berkeley, Berkeley, United States shows that “Dnmt3a is an epigenetic mediator of adipose insulin resistance.”…

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