Ideas

March 28, 2019

Molecular therapy for tuberculosis (TB): Clioquinol[iodochlorhydroxyquin] (Trade name:Cortin),  an antifungal and antiprotozoal drug that inhibits certain enzymes related to DNA replication, deacetylates RelA/p65, inhibits inflammatory gene expression downstream of RelA/p65, inhibits TB pathogenesis, increases the efficacy of anti-TB drug, and promotes M. tuberculosis clearance via upregulation of its target gene, 28/March/2019, 5.47 am

Introduction: What they say: A study from the Singapore Immunology Network, Agency for Science, Technology and Research, Singapore; and Lee Kong Chian School of Medicine, Nanyang […]
March 26, 2019

A sweet way to stay free of TIIDM: Trehalose, a disaccharide and artificial sweetener found in mushroom and others, increases Pax6 and insulin expression, decreases the levels of glucagon, ghrelin and Somatostatin, reduces metabolic stress, improves insulin sensitivity, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 26/May/2019, 11.48 pm

Introduction: What they say A study from the Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, […]
March 26, 2019

Intracardiac injection of Erythropoietin/Hematopoietin protects against Myocardial infarction: Erythropoietin inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction, via up-regulation of PNUTS, 26/March/2019, 11.39 pm

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published, in the 7 March  2013 issue of of […]
March 26, 2019

Repurposing the anti-bacterial agent Ciprofloxacin as an antiviral agent: Ciprofloxacin-based antiviral therapy for chikungunya (CHIKV) and Zika (ZIKV) viruses: Ciprofloxacin (brand name: Ciloxan, Cipro, Neofloxin) increases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication, via upregulation of its target gene, 26/March/2019, 11.23 pm

Introduction: What they say A study from the Viral Populations and Pathogenesis Unit, Institut Pasteur, CNRS UMR 3569, 25–28 rue du Dr. Roux, 75724 Paris Cedex […]
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