Ideas

Low-salt diet shuts-off perception of pain: Mechanistic insights into how caloric restriction functions as a pain medication:  Low-salt diet (0.075%) increases the expression of PD-L1, attenuates acute and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability, via up-regulation of its target gene, 29/April/2019, 10.04  pm
Low-salt diet shuts-off perception of pain: Mechanistic insights into how caloric restriction functions as a pain medication:  Low-salt diet (0.075%) increases the expression of PD-L1, attenuates acute and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability, via up-regulation of its target gene, 29/April/2019, 10.04  pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain Science, Fudan University,…

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Neuropeptide Y-based therapy for inflammation and arthritis: Neuropeptide Y, a  36 amino-acid neuropeptide that plays a role in the regulation of food intake, storage of food, anxiety, stress, perception of pain and others, increases IL-9 levels, augments proliferation of ILC2s (type 2 innate lymphoid cells) and regulatory T (Treg) cells, promotes resolution of inflammation, attenuates cartilage destruction, decreases bone loss, and inhibits pathological features associated with arthritis via up-regulation of its target genes, 29/April/2019, 3.10 pm
Neuropeptide Y-based therapy for inflammation and arthritis: Neuropeptide Y, a  36 amino-acid neuropeptide that plays a role in the regulation of food intake, storage of food, anxiety, stress, perception of pain and others, increases IL-9 levels, augments proliferation of ILC2s (type 2 innate lymphoid cells) and regulatory T (Treg) cells, promotes resolution of inflammation, attenuates cartilage destruction, decreases bone loss, and inhibits pathological features associated with arthritis via up-regulation of its target genes, 29/April/2019, 3.10 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from Department of Internal Medicine 3-Rheumatology and Immunology, Friedrich Alexander University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany shows that “Resolution of inflammation by…

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Oxyntomodulin-based therapy for lowering cholesterol, and triglycerides levels: Oxyntomodulin (OXM), a 37 amino acid intestinal peptide that  inhibits food intake and body weight, decreases the levels of HMGCR,  triglycerides, free cholesterol, and total cholesterol and prevents the progression of Non-alcoholic fatty liver disease (NAFLD), via up-regulation of its target gene, 29/April/2019, 2.58 pm
Oxyntomodulin-based therapy for lowering cholesterol, and triglycerides levels: Oxyntomodulin (OXM), a 37 amino acid intestinal peptide that  inhibits food intake and body weight, decreases the levels of HMGCR,  triglycerides, free cholesterol, and total cholesterol and prevents the progression of Non-alcoholic fatty liver disease (NAFLD), via up-regulation of its target gene, 29/April/2019, 2.58 pm 960 720 Dr Boomi's Genom-2-Discovery Center

The significance of the study: Given that: (1)  15-30% of Western populations suffer from Non-alcoholic fatty liver disease (NAFLD), while 6-25% of Asian populations suffer from it; (2) 75 to 100 million people…

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Caloric restriction restricts perception of pain: Mechanistic insights into how caloric restriction functions as a pain medication:  Caloric restriction increases the expression of PD-L1, attenuates acute and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability, via up-regulation of its target gene, 29/April/2019, 2.47 pm
Caloric restriction restricts perception of pain: Mechanistic insights into how caloric restriction functions as a pain medication:  Caloric restriction increases the expression of PD-L1, attenuates acute and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability, via up-regulation of its target gene, 29/April/2019, 2.47 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain Science, Fudan University,…

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Empty-stomach intelligence is explained: Mechanistic insights into how hunger hormone Ghrelin augments augments memory, learning, and cognition:  Ghrelin, a digestive hormone that controls appetite,  increases Tissue inhibitor of metalloproteinases 2 (TIMP2) and BDNF levels, improves cognition, and attenuates age-associated decline in memory and learning, via up-regulation of its target genes, 28/April/2018, 12.17 am
Empty-stomach intelligence is explained: Mechanistic insights into how hunger hormone Ghrelin augments augments memory, learning, and cognition:  Ghrelin, a digestive hormone that controls appetite,  increases Tissue inhibitor of metalloproteinases 2 (TIMP2) and BDNF levels, improves cognition, and attenuates age-associated decline in memory and learning, via up-regulation of its target genes, 28/April/2018, 12.17 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California 94305, USA;  Paul F. Glenn Center for the Biology of…

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Natural product-based therapy for anxiety and depression: Paeonol, isolated from Paeonia suffruticosa,  decreases PHF8 levels, increases the expression of serotonin receptors Htr1a and Htr2a, and promotes resistance to stress-induced -anxiety and -depression, via down-regulation of its target gene, 27/April/2019, 12.05 am
Natural product-based therapy for anxiety and depression: Paeonol, isolated from Paeonia suffruticosa,  decreases PHF8 levels, increases the expression of serotonin receptors Htr1a and Htr2a, and promotes resistance to stress-induced -anxiety and -depression, via down-regulation of its target gene, 27/April/2019, 12.05 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say:  A study from Department of Molecular Biology, Cancer Center and Center for Regenerative Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA; Department of Stem Cell and…

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