Ideas

Natural product therapy for Myocardial Infarction: Ampelopsin (AMP), a flavnol mainly found in Ampelopsis grossedentata (commonly known as Mayeam), improves myocardial function after myocardial infarction via up regulation of PNUTS/PPP1R10 (Serine/threonine-protein phosphatase 1 regulatory subunit 10), 28/October/2016, 10.29 am
Natural product therapy for Myocardial Infarction: Ampelopsin (AMP), a flavnol mainly found in Ampelopsis grossedentata (commonly known as Mayeam), improves myocardial function after myocardial infarction via up regulation of PNUTS/PPP1R10 (Serine/threonine-protein phosphatase 1 regulatory subunit 10), 28/October/2016, 10.29 am 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, Boon, and others. On the foundation of…

read more

Anti-telomerase cancer therapy: Bisindole-PBD (Compound 5b) suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) and inhibits cancer progression via down-regulation of its target gene, 28/October/2016, 9.00 am
Anti-telomerase cancer therapy: Bisindole-PBD (Compound 5b) suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) and inhibits cancer progression via down-regulation of its target gene, 28/October/2016, 9.00 am 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: The 1989 Nobel prize winner in Chemistry, Prof. Thomas R. Cech from the BioFrontiers Institute, USA has published a research paper in the 13 December 2012 Nature (492(7428):285-9; and I.F: >42) stating that “The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity.”  This study provides mechanistic…

read more

Molecular therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: NURR1 promotes an insulin-sensitized state via up-regulation of reprogramming protein Lin28, 28/October/2016, 8.18 am
Molecular therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: NURR1 promotes an insulin-sensitized state via up-regulation of reprogramming protein Lin28, 28/October/2016, 8.18 am 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows that “The Lin28/let-7 axis regulates glucose metabolism.” This study was…

read more

Natural product-based Combination therapy for Lifespan extension: Green tea extract and Curcumin combo increases life span via up-regulation of its target gene BubR1, 27/October/2016, 2.54 pm
Natural product-based Combination therapy for Lifespan extension: Green tea extract and Curcumin combo increases life span via up-regulation of its target gene BubR1, 27/October/2016, 2.54 pm 150 150 Dr Boomi's Genom-2-Discovery Center

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and Department of Pharmacology, School…

read more

Molecular therapy for Myocardial Infarction: BMB2 (Bone morphogenetic protein 2) improves myocardial function after myocardial infarction via up-regulation of PNUTS/PPP1R10 (Serine/threonine-protein phosphatase 1 regulatory subunit 10), 27/October/2016, 12.29 pm
Molecular therapy for Myocardial Infarction: BMB2 (Bone morphogenetic protein 2) improves myocardial function after myocardial infarction via up-regulation of PNUTS/PPP1R10 (Serine/threonine-protein phosphatase 1 regulatory subunit 10), 27/October/2016, 12.29 pm 150 150 Dr Boomi's Genom-2-Discovery Center

A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, Boon, and others. On the foundation of this…

read more

Natural product-based PD-1 pathway blockade for Human cancer therapy: Isorhapontigenin, isolated from Aiphanes Aculeata, Norway/Sitka/White Spruce, inhibits the expression of co-inhibitory receptor PD-1 on Antigen- Specific T-cells, increases the production of cytokines by tumor-infiltrating lymphocytes (TIL), and draining lymph nodes and augments anti-tumor activity via down-regulation of its target gene, 27/october/2016, 8.18 am
Natural product-based PD-1 pathway blockade for Human cancer therapy: Isorhapontigenin, isolated from Aiphanes Aculeata, Norway/Sitka/White Spruce, inhibits the expression of co-inhibitory receptor PD-1 on Antigen- Specific T-cells, increases the production of cytokines by tumor-infiltrating lymphocytes (TIL), and draining lymph nodes and augments anti-tumor activity via down-regulation of its target gene, 27/october/2016, 8.18 am 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction:What they say: A recent study from Division of Infectious Diseases, School of Medicine, Johns Hopkins University, Baltimore, MD 21218, United States shows that “TGF-β1-Mediated Smad3 Enhances PD-1 Expression on…

read more
Start Typing