Ideas

Natural product therapy for tuberculosis: Cucurbitacin E, found abundantly in Watermelons, among others, increases the expression of MKP-1, inhibits TLR2 signalling, secretion of Chemokine CXCL5, and recruitment of polymorphonuclear leukocytes (PMNs), decreases destructive pulmonary inflammation, promotes M. tuberculosis clearance and inhibits pulmonary tuberculosis via up-regulation of its target gene, 27/October/2016, 7.37 am
Natural product therapy for tuberculosis: Cucurbitacin E, found abundantly in Watermelons, among others, increases the expression of MKP-1, inhibits TLR2 signalling, secretion of Chemokine CXCL5, and recruitment of polymorphonuclear leukocytes (PMNs), decreases destructive pulmonary inflammation, promotes M. tuberculosis clearance and inhibits pulmonary tuberculosis via up-regulation of its target gene, 27/October/2016, 7.37 am 150 150 Dr Boomi's Genom-2-Discovery Center

A study from the Max Plank Institute for Infection Biology, Berlin, Germany shows that “CXCL5-secreting pulmonary epithelial cells drive destructive neutrophilic inflammation in tuberculosis.” This study was published in the…

read more

Natural product anti-inflammatory therapy for upper respiratory tract inflammatory diseases: Berberine increases the expression of negative regulator of inflammation MyD88(s), inhibits pro-inflammatory mediators in lungs, and alleviates the common respiratory pathogen nontypeable Haemophilus influenzae (NTHi)-exacerbated asthma & chronic obstructive pulmonary disease via up-regulation of its target gene, 27/October/2015, 6.33 am
Natural product anti-inflammatory therapy for upper respiratory tract inflammatory diseases: Berberine increases the expression of negative regulator of inflammation MyD88(s), inhibits pro-inflammatory mediators in lungs, and alleviates the common respiratory pathogen nontypeable Haemophilus influenzae (NTHi)-exacerbated asthma & chronic obstructive pulmonary disease via up-regulation of its target gene, 27/October/2015, 6.33 am 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction:  A study from the Center for Inflammation, Immunity &Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, 30303, USA shows that: “Resveratrol suppresses NTHi-induced inflammation via up-regulation of…

read more

Molecular therapy for Myocardial dysfunction: MiR-296 increases CDK inhibitor p27 expression, inhibits mTOR pathway, promotes autophagy in myocardial cells and prevents myocardial dysfunction via down-regulation of its target gene, 27/October/2016, 6.17 am
Molecular therapy for Myocardial dysfunction: MiR-296 increases CDK inhibitor p27 expression, inhibits mTOR pathway, promotes autophagy in myocardial cells and prevents myocardial dysfunction via down-regulation of its target gene, 27/October/2016, 6.17 am 150 150 Dr Boomi's Genom-2-Discovery Center

Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports here that: Molecular therapy for Myocardial dysfunction: MiR-296 increases CDK inhibitor p27 expression, inhibits mTOR pathway, promotes autophagy in myocardial cells and prevents myocardial…

read more

Natural product Lifespan extension therapy: Isorhapontigenin, isolated from Aiphanes Aculeata, Norway/Sitka/white Spruce, among others, increases life span via up-regulation of its target gene BubR1, 26/October/2016, 3.18 pm
Natural product Lifespan extension therapy: Isorhapontigenin, isolated from Aiphanes Aculeata, Norway/Sitka/white Spruce, among others, increases life span via up-regulation of its target gene BubR1, 26/October/2016, 3.18 pm 150 150 Dr Boomi's Genom-2-Discovery Center

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and Department of Pharmacology, School…

read more

Natural product therapy for brain repair and Life-span extension: Resveratrol, an activator of longevity promoting gene Sirtuin-1, increases VGF and BDNF expression, promotes Oligodendrocytes (OP) proliferation, triggers myelination on neurons, reverts neural damage, produces anti-depressant like effects, and prolongs lifespan via up-regulation of its target gene, 26/October/2016, 7.10 am
Natural product therapy for brain repair and Life-span extension: Resveratrol, an activator of longevity promoting gene Sirtuin-1, increases VGF and BDNF expression, promotes Oligodendrocytes (OP) proliferation, triggers myelination on neurons, reverts neural damage, produces anti-depressant like effects, and prolongs lifespan via up-regulation of its target gene, 26/October/2016, 7.10 am 150 150 Dr Boomi's Genom-2-Discovery Center

What they say: Introduction:   A recent study from the Department of Biochemistry & Molecular Pharmacology, Smilow Research Center, Howard Hughes Medical Institute, NYU School of Medicine, 522 First Avenue,…

read more

Natural product therapy targeting aberrant Lipid synthesis in Human cancers: Thymoquinone, isolated from Monarda Fistulosa, suppresses the expression of the principal enzyme in lipid synthesis, ACLY, inhibits aberrant lipid production, and tumor progression via up-regulation of its target gene, 26/October/2016, 6.00 am
Natural product therapy targeting aberrant Lipid synthesis in Human cancers: Thymoquinone, isolated from Monarda Fistulosa, suppresses the expression of the principal enzyme in lipid synthesis, ACLY, inhibits aberrant lipid production, and tumor progression via up-regulation of its target gene, 26/October/2016, 6.00 am 150 150 Dr Boomi's Genom-2-Discovery Center

A recent study from Rutgers Cancer Institute of New Jersey, Rutgers University, The State University of New Jersey, New Brunswick, New Jersey, USA shows that “Cullin3–KLHL25 ubiquitin ligase targets ACLY for…

read more
Start Typing