Ideas

March 3, 2017
Published by admin_auro at March 3, 2017
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Natural product-derived therapy for EVI-1-Overexpressing Acute Myeloid Leukemia: Naringenin, isolated from Grapefruit, decreases the expression of MECOM/EVI-1 and its down target genes, including CKMT-1, alters Arginine-creatine metabolism, inhibits mitochondrial respiration, depletes ATP levels, and promotes regression of EVI-1-overexpressing AML via up regulation of its target gene, 3/March/2017, 10.53 pm

Introduction: What they say: A study from the Koch Institute for Integrative Cancer Research at Massachusetts Institute of Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA; […]
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March 3, 2017
Published by admin_auro at March 3, 2017
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Natural product-derived therapy for glucose homeostasis and TIIDM: Fisetin, isolated from strawberries, apples, persimmons, onions, cucumbers, acacias and among others, increases Barr2 expression, augments the functional activity of CAMKII, increases insulin secretion, promotes glucose homeostasis, prevents progression to TIIDM and ameliorates obesity-associated metabolic deficits via down regulation of its target gene, 3/March/2017, 3.35 pm

Introduction: What they say A study from the Molecular Signaling Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland […]
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March 3, 2017
Published by admin_auro at March 3, 2017
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Amino acid therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: L-Leucine, an essential amino acid, increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state via up-regulation of its target gene, 3/March/2017, 7.31 am

Introduction: What they say:  A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows that “The […]
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March 3, 2017
Published by admin_auro at March 3, 2017
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Molecular therapy for Metastatic cancers: Prodigiosin decreases the expression of PPM22 and inhibits migration, invasion and metastasis of cancer cells via up regulation of its target gene, 3/March/2017, 5.57 am

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]
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