Ideas

July 4, 2017

Natural product-derived therapy for Metastatic cancers: Dihydroartemisinin (DHA), a derivative of Artemisinin isolated from Artemisia Annua L, increases the expression of metastasis/tumor suppressors BTG2 and INK4a, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 5/July/2017, 1.00 am

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more than half […]
July 4, 2017

Low-intensity Electrical stimulation-based regenerative therapy for muscular atrophy: Low-intensity Electrical stimulation wave therapy increases the expression of IGF-1, PI3K(p85a) and B-Myb, decreases the expression of tumor suppressors, promotes regeneration of muscle cells, and reverses muscle atrophy via up regulation of its target gene, 5/July/2017, 12.39 am

Introduction: What they say A study from the Cardiac Regeneration and Ageing Lab, School of Life Science, Shanghai University, Shanghai 200444, China shows that “miR-29b contributes to multiple types of muscle […]
July 4, 2017

Natural product-based therapy for Regenerating the lost cardiomyocytes in Myocardial patients: Celastrol, isolated from Thunder God Vine, increases the expression of ERBB2/Her2 and promotes dedifferentiation of cardiomyocytes via down regulation of its target gene, 5/July/2017, 12.31 am

Introduction: What they say A recent study from the Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel shows that “ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation.” This study was […]
July 4, 2017

Natural product-derived therapy for muscle atrophy and wasting: L-Leucine, an essential branched chain amino acid, increases the expression of FGF19 and its receptor ß-Klotho, phosphorylates ERK1/2 and S6K1, decreases the expression of tumor suppressors genes, promotes regeneration of muscle cells and hypertrophy of skeletal muscle, and reverses muscular atrophy and wasting via up regulation of its target gene, 5/July/2017, 12.24 am

Introduction: What they say A study from Department of Biology, University of Bergen, Bergen, Norway; and Univ-Lyon, CarMeN Laboratory, INSERM 1060, INRA 1397, Université Claude Bernard […]
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