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Ideas

January 16, 2017

Natural product-derived therapy for Human Leukemias: Manumycin A, an antibiotic that acts as an inhibitor of farnesyltransferase (FTase), suppresses B-Cell and myeloid leukemias via up regulation of the tumor suppressor IRF4, 16/January/2016, 11.45 pm

Introduction: What they say Noble laureate in Physiology/Medicine (1975) Prof. David Baltimore, from California Institute of Technology, California, USA, had reported in the July 8, 2014 issue of the Journal “Blood” that: “Dual mechanisms […]
January 16, 2017

Fish oil therapy for glucose homeostasis and TIIDM: Docosahexaenoic acid (DHA), found in fish oil and algae oil among others, increases Pax6 and insulin expression, decreases the levels of glucagon, ghrelin and Somatostatin, reduces metabolic stress, improves insulin sensitivity, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 16/January/2017, 11.21 pm

Introduction: What they say A study from the Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, […]
January 16, 2017

Natural product-derived therapy for Metastatic human tumors: β-Asarone (1-propenyl-2,4,5-methoxybenzol), found in herb Acorus calamus Linn, inhibits the expression of a number of enzymes in glycolytic cycle, and suppresses proliferation, migration, invasion, tumorigenesis and metastasis via up regulation of its target gene, 16/January/2017, 10.50 pm

Introduction: What they say: A study from the State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen […]
January 16, 2017

Anticancer therapy targeting the cancer stem cells: MiRNA-9600 inhibits the expression of stem cell gene/reprogramming protein Sox2, suppresses proliferation, and promotes apoptosis of cancer cells via down regulation of its target gene, 16/January/2016, 10.14 pm

Research findings to Therapeutic opportunity:   The study presented here suggests that MiRNA-9600, by increasing the expression of its target genes, it may decrease the expression of the protein that […]
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