Ideas

A sweet way to stay free of cardiac diseases: Sugar-based Regenerative therapy for regaining the lost cardiomyocytes in Myocardial patients:  Trehalose, an artificial sweetener composed of two glucose molecules,  increases the expression of ERBB2/Her2 and promotes dedifferentiation  of cardiomyocytes, via up-regulation of its target gene, 26/March/2018, 10.29 pm
A sweet way to stay free of cardiac diseases: Sugar-based Regenerative therapy for regaining the lost cardiomyocytes in Myocardial patients:  Trehalose, an artificial sweetener composed of two glucose molecules,  increases the expression of ERBB2/Her2 and promotes dedifferentiation  of cardiomyocytes, via up-regulation of its target gene, 26/March/2018, 10.29 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A recent study from the Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel shows that “ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation.” This study was published, in the 6 April…

read more

Molecular Hydrogen gas-based therapy for heart regeneration and repair: Intracardiac or subcutaneous injection of Hydrogen gas decreases tumor suppressor MiR-128 and cyclin-dependent kinase inhibitor p27 expression, increases SUZ12 expression, increases Cyclin E and CDK2 expression, promotes proliferation/re-entry of postnatal/adult cardiomyocytes, attenuates fibrosis, ameliorates cardiac dysfunction, and promotes heart repair in response to myocardial infarction, via up-regulation of its target gene, 25/March/2019, 2.18 pm
Molecular Hydrogen gas-based therapy for heart regeneration and repair: Intracardiac or subcutaneous injection of Hydrogen gas decreases tumor suppressor MiR-128 and cyclin-dependent kinase inhibitor p27 expression, increases SUZ12 expression, increases Cyclin E and CDK2 expression, promotes proliferation/re-entry of postnatal/adult cardiomyocytes, attenuates fibrosis, ameliorates cardiac dysfunction, and promotes heart repair in response to myocardial infarction, via up-regulation of its target gene, 25/March/2019, 2.18 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A recent study from Department of Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, 45267, USA; Key Laboratory of Molecular Target and…

read more

Repurposing the antibiotic Ciprofloxacin into a broad-spectrum anti-infective agent: Ciprofloxacin, a drug used to treat bacterial infections,  inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1,  respiratory syncytial,  Sindbis, and SFV viruses by increasing the Levels of the Antiviral Proteins IFITM3, & Interferon-stimulated gene 15, 25/March/2019, 8.42 am
Repurposing the antibiotic Ciprofloxacin into a broad-spectrum anti-infective agent: Ciprofloxacin, a drug used to treat bacterial infections,  inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1,  respiratory syncytial,  Sindbis, and SFV viruses by increasing the Levels of the Antiviral Proteins IFITM3, & Interferon-stimulated gene 15, 25/March/2019, 8.42 am 1280 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A study from the Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard Medical School, Charlestown, MA 02129, USA shows that “The IFITM proteins…

read more

Intracardiac injection of Hydrogen gas protects against cardiac hypertrophy and fibrosis: Intracardiac or subcutaneous injection or inhalation of Hydrogen gas decreases MiR-29 expression, activates wnt- signaling and its components GSK3B, ICAT/CTNNBIP1, HBP1, and GLIS2, attenuates pathologic hypertrophy, inhibits fibrosis of the heart tissue, and improves cardiac function via upregulation of its target gene, 25/March/2019, 8.22 am
Intracardiac injection of Hydrogen gas protects against cardiac hypertrophy and fibrosis: Intracardiac or subcutaneous injection or inhalation of Hydrogen gas decreases MiR-29 expression, activates wnt- signaling and its components GSK3B, ICAT/CTNNBIP1, HBP1, and GLIS2, attenuates pathologic hypertrophy, inhibits fibrosis of the heart tissue, and improves cardiac function via upregulation of its target gene, 25/March/2019, 8.22 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say:   A recent study from the Institute of Pharmacology and Toxicology, Technical University Munich (TUM), 80802, Munich, Germany; DZHK (German Center for Cardiovascular Research), partner site Munich…

read more

Repurposing the anti-bacterial agent Enoxacin into an antiviral agent: Enoxacin-based antiviral therapy for chikungunya (CHIKV) and Zika (ZIKV) viruses: Enoxacin (Trade names: Comprecin, Enoksetin, Enoxen, Enroxil, Enoxin, Enoxor, Flumark and others),  a fluoroquinolone-based antibiotic commonly used in the treatment of urinary tract infections and gonorrhea, increases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication, via upregulation of its target gene, 25/March/2019, 7.54 am
Repurposing the anti-bacterial agent Enoxacin into an antiviral agent: Enoxacin-based antiviral therapy for chikungunya (CHIKV) and Zika (ZIKV) viruses: Enoxacin (Trade names: Comprecin, Enoksetin, Enoxen, Enroxil, Enoxin, Enoxor, Flumark and others),  a fluoroquinolone-based antibiotic commonly used in the treatment of urinary tract infections and gonorrhea, increases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication, via upregulation of its target gene, 25/March/2019, 7.54 am 1280 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Viral Populations and Pathogenesis Unit, Institut Pasteur, CNRS UMR 3569, 25–28 rue du Dr. Roux, 75724 Paris Cedex 15, France shows that…

read more

Ribonucleic acid-based therapy for cardiomyocyte proliferation and heart regeneration: LncRNA ROR decreases tumor suppressor MiR-128 and cyclin-dependent kinase inhibitor p27 expression, increases SUZ12 expression, increases Cyclin E and CDK2 expression, promotes proliferation/re-entry of postnatal/adult cardiomyocytes, attenuates fibrosis, ameliorates cardiac dysfunction, and promotes heart repair in response to myocardial infarction, via up-regulation of its target gene, 24/March/2019, 5.22 pm
Ribonucleic acid-based therapy for cardiomyocyte proliferation and heart regeneration: LncRNA ROR decreases tumor suppressor MiR-128 and cyclin-dependent kinase inhibitor p27 expression, increases SUZ12 expression, increases Cyclin E and CDK2 expression, promotes proliferation/re-entry of postnatal/adult cardiomyocytes, attenuates fibrosis, ameliorates cardiac dysfunction, and promotes heart repair in response to myocardial infarction, via up-regulation of its target gene, 24/March/2019, 5.22 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A recent study from Department of Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, 45267, USA; Key Laboratory of Molecular Target and…

read more
Start Typing