Ideas

Anti-infective Therapy: Anisomycin, a pyrrolidine antibiotic that functions a protein synthesis inhibitor,  inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1,  respiratory syncytial,  Sindbis, and SFV viruses by increasing the Levels of the Antiviral Proteins IFITM3, & Interferon-stimulated gene 15, 24/March/2019, 5.08 pm
Anti-infective Therapy: Anisomycin, a pyrrolidine antibiotic that functions a protein synthesis inhibitor,  inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1,  respiratory syncytial,  Sindbis, and SFV viruses by increasing the Levels of the Antiviral Proteins IFITM3, & Interferon-stimulated gene 15, 24/March/2019, 5.08 pm 1280 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A study from the Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard Medical School, Charlestown, MA 02129, USA shows that “The IFITM proteins…

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Ribonucleic acid-based therapy for cardiac hypertrophy and fibrosis: LncRNA ROR decreases MiR-29 expression, activates Wnt- signaling and its components GSK3B, ICAT/CTNNBIP1, HBP1 and GLIS2, attenuates pathologic hypertrophy, inhibits fibrosis of the heart tissue, and improves cardiac function, via upregulation of its target gene, 24/March/2019, 4.31 pm
Ribonucleic acid-based therapy for cardiac hypertrophy and fibrosis: LncRNA ROR decreases MiR-29 expression, activates Wnt- signaling and its components GSK3B, ICAT/CTNNBIP1, HBP1 and GLIS2, attenuates pathologic hypertrophy, inhibits fibrosis of the heart tissue, and improves cardiac function, via upregulation of its target gene, 24/March/2019, 4.31 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A recent study from the Institute of Pharmacology and Toxicology, Technical University Munich (TUM), 80802, Munich, Germany; DZHK (German Center for Cardiovascular Research), partner site Munich…

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Mechanistic insights into how exercise may ameliorate Diabetes Mellitus: Physical exercise augments the expression of FGF19 and FGF1,  attenuates hepatic glucose production, decreases hepatic acetyl CoA content, brings down the levels of plasma ACTH, and corticosterone, augments insulin sensitivity, promotes weight loss and alleviates TIDM, via upregulation of its target gene, 23/March/2019, 7.19 pm
Mechanistic insights into how exercise may ameliorate Diabetes Mellitus: Physical exercise augments the expression of FGF19 and FGF1,  attenuates hepatic glucose production, decreases hepatic acetyl CoA content, brings down the levels of plasma ACTH, and corticosterone, augments insulin sensitivity, promotes weight loss and alleviates TIDM, via upregulation of its target gene, 23/March/2019, 7.19 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say  A study from Diabetes and Obesity Center of Excellence, Department of Medicine, University of Washington, Seattle, Washington, USA shows that Central injection of FGF1 induces sustained…

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Interleukin-based Anti-infective Therapy: IL-24  inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1,  respiratory syncytial,  Sindbis, and SFV viruses by increasing the Levels of the Antiviral Proteins IFITM3, & Interferon-stimulated gene 15, 23/March/2019, 7.04 pm
Interleukin-based Anti-infective Therapy: IL-24  inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1,  respiratory syncytial,  Sindbis, and SFV viruses by increasing the Levels of the Antiviral Proteins IFITM3, & Interferon-stimulated gene 15, 23/March/2019, 7.04 pm 1280 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A study from the Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard Medical School, Charlestown, MA 02129, USA shows that “The IFITM proteins…

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Ethyl pyruvate-based therapy for diabetes:  Ethyl pyruvate decreases DNA-PPK expression, suppresses phosphorylation of HSP90a, increases AMPK activity, augments mitochondrial biogenesis and energy metabolism, promotes weight loss and exercise endurance and alleviates TIIDM, via down-regulation of its target gene, 22/March/2019, 8.55 am
Ethyl pyruvate-based therapy for diabetes:  Ethyl pyruvate decreases DNA-PPK expression, suppresses phosphorylation of HSP90a, increases AMPK activity, augments mitochondrial biogenesis and energy metabolism, promotes weight loss and exercise endurance and alleviates TIIDM, via down-regulation of its target gene, 22/March/2019, 8.55 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Laboratory of Obesity and Aging Research, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA; and Laboratory…

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A gaseous way to keep cardiac diseases at bay: Hydrogen gas-based cardiac rejuvenation therapy: Inhalation  or Subcutaneous injection of hydrogen gas suppresses tumor suppressor INK4a/p16 expression, and inhibits dilated cardiomyopathy, via up regulation of its target gene, 22/March/2019, 8.40 am
A gaseous way to keep cardiac diseases at bay: Hydrogen gas-based cardiac rejuvenation therapy: Inhalation  or Subcutaneous injection of hydrogen gas suppresses tumor suppressor INK4a/p16 expression, and inhibits dilated cardiomyopathy, via up regulation of its target gene, 22/March/2019, 8.40 am 960 720 Dr Boomi's Genom-2-Discovery Center

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: A gaseous way to keep cardiac diseases at bay: Hydrogen gas-based cardiac rejuvenation therapy: Inhalation  or Subcutaneous…

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