Ideas

March 29, 2019

Published by admin_auro at March 29, 2019

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Intracardiac injection of Erythropoietin/Hematopoietin promotes heart regeneration and repair: Intracardiac injection of Erythropoietin/Hematopoietin decreases tumor suppressor MiR-128 and cyclin-dependent kinase inhibitor p27 expression, increases SUZ12 expression, increases Cyclin E and CDK2 expression, promotes proliferation/re-entry of postnatal/adult cardiomyocytes, attenuates fibrosis, ameliorates cardiac dysfunction, and promotes heart repair in response to myocardial infarction, via up-regulation of its target gene, 30/March/2019, 12.20 am

Introduction: What they say: A recent study from Department of Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, 45267, USA; Key Laboratory […]

March 29, 2019

Published by admin_auro at March 29, 2019

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Intracardiac/Epicardial injection of Erythropoietin/Hematopoietin may attenuate pathogenesis-associated with Myocardial infarction: Erythropoietin/Hematopoietin decreases GM-CSF (Granulocyte-macrophage colony-stimulating factor) expression, inhibits undue leucocyte activation and invasion, suppresses recruitment of inflammatory cells, inhibits left ventricular rupture, and promotes heart healing via up regulation of its target gene, 30/March/2019, 12.04 am

Introduction: What they say: A recent study from Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; and Center for Systems […]

March 29, 2019

Published by admin_auro at March 29, 2019

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Cancer
Ideas

Probiotic-based chemotherapy targeting cancer stem cells and immune-inhibitory receptors in advanced metastatic cancers: A pharmaceutical mixture encompassing a pharmacological formulation encompassing Metformin, Navitoclax/ABT-263, & Dasatinib (MND) and probiotic Lactobacillus rhamnosus increases the expression of tumor suppressor genes, such as RECK, BTG2, p53, and TA-p73/p63, inhibits immune-inhibitory receptors/molecules, targets cancer stem cells, confers protection against chemoresistance and prolongs survival, via up-regulation of its target gene, 29/March/2019, 11.04 pm

What we say: On the foundation of this interesting finding, Dr L Boominathan PhD, the Director-cum-chief Scientist of GBMD, reports that: Probiotic-based chemotherapy targeting cancer stem cells […]

March 29, 2019

Published by admin_auro at March 29, 2019

Categories

Repurposing the antihyperglycemic drug into an anti-glaucoma agent: Metformin, the widely prescribed drug in the treatment of TIIDM, increases Nmnat1 expression, increases NAD+ levels, improves neuronal dysfunction, and protects against glaucoma, via down regulation of its target gene, 29/March/2019, 10.53 am

Introduction: What they say A study from the The Jackson Laboratory, Bar Harbor, ME 04609, USA; Department of Ophthalmology, Tufts University of Medicine, Boston, MA 02111, […]