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Ideas

July 25, 2018

Unknown function of a known vaccine in the treatment of muscle atrophy and wasting: TB/BCG vaccine,  a tuberculosis vaccine,  increases the expression of FGF19 and its receptor ß-Klotho, phosphorylates ERK1/2 and S6K1, decreases the expression of tumor suppressors  genes, promotes regeneration of muscle cells and hypertrophy of skeletal muscle, and reverses muscular atrophy and wasting, via upregulation of its target gene, 25/July/2018, 11.49 pm

Introduction: What they say A study from Department of Biology, University of Bergen, Bergen, Norway; and Univ-Lyon, CarMeN Laboratory, INSERM 1060, INRA 1397, Université Claude Bernard […]
July 25, 2018

Vaccinate yourself with TB vaccine to lead a pain-free life: TB/BCG vaccine-based activation of the PD-1 pathway for Pain therapy: TB/BCG vaccine, a tuberculosis vaccine,  increases the expression of PD-L1, attenuates acute and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability, via up-regulation of its target gene, 25/July/2018, 11.20 pm

 Introduction: What they say: A recent study, from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for […]
July 24, 2018

Vasoactive intestinal polypeptide (VIP)-based therapy for blood sugar disease (autoimmune diabetes (TIDM)): Vasoactive intestinal polypeptide (VIP), a peptide hormone known to play a role in heart contractility, vasodilation, and blood pressure,  increases PD-L1 expression,  augments Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up-regulation of its target gene, 24/July/2018,  10.24 pm

Introduction: What they say A study from the International Center for T1D, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, “L. Sacco” Department of Biomedical and […]
July 23, 2018

A sweet way to lengthen lifespan: Astragalus polysaccharide, isolated from astragalus membraneous,  may  increase insulin sensitivity, slow down cardiac aging, and increase lifespan, via up-regulation of BubR1 and others genes, 23/July/2018, 11.58 pm

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and […]
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