Infectious diseases

February 14, 2019

Immune enhancement therapy: Ezetimibe, a drug used in the treatment of dyslipidemia, increases SOX2 expression, and promotes innate immunity against bacterial infection, via down-regulation of its target gene, 14/February/2019, 6.41 am

Introduction: What they say:   A recent study from the Institute of Biophysics, Chinese Academy of Sciences, Beijing, China shows that “Sox2 functions as a sequence-specific DNA sensor in […]
October 26, 2018

Dealing harmful infective agents with Probiotics (good bacteria):  Probiotics-based adjuvant therapy for viral and bacterial infections: Probiotic Lactobacillus crispatus inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1,  respiratory syncytial,  Sindbis, and SFV viruses by increasing the Levels of the antiviral Proteins IFITM3, & Interferon-stimulated gene, 26/October/2018, 7.19 am

Introduction: What they say: A study from the Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard Medical School, Charlestown, MA 02129, USA […]
July 21, 2017

Antiviral therapy against Neuroinvasive West Nile virus: Metformin, the widely used drug in the treatment of TIIDM, increases the expression of RIPK3, promotes chemokines production, inhibits neuroinflammation, and restricts neuroinvasive West Nile virus production and pathogenesis in neurons via up regulation of its target gene, 22/July/2017, 12.08 am

Introduction: What they say A study from the Department of Immunology, University of Washington, Seattle, WA 98109, USA; Center for Innate Immunity and Immune Disease, University of […]
June 12, 2017

Natural product-derived therapy for tuberculosis: Atractylenolide III, isolated from Atractylodes ovata, deacetylates RelA/p65, inhibits inflammatory gene expression downstream of RelA/p65, inhibits TB pathogenesis, increases the efficacy of anti-TB drug, and promotes M. tuberculosis clearance via up regulation of its target gene, 12/June/2017, 11.37 pm

Introduction: What they say: A study from the Singapore Immunology Network, Agency for Science, Technology and Research, Singapore; and Lee Kong Chian School of Medicine, Nanyang […]