Longevity

October 24, 2018

Anti-hypertensive drug Amlodipine for an enhanced, extended, and healthy lifespan: Amlodipine (trade name: Norvasc) increases NMN/NAD levels, decreases interaction of DBC1 with PARP1, increases PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer, and aging, via down-regulation of its target gene, 24/October/2018, 10.46 pm

Introduction: What they say A study from Department of Genetics, Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA, USA; and […]
September 30, 2018

Mechanistic insights into how probiotic Lactobacillius gasseri SBT2055 (LG2055) functions as a longevity-promoter: Probiotic Lactobacillius gasseri SBT2055 (LG2055) increases CHIP levels, increases monoubiquitylation of insulin receptor (INSR), decreases INSR protein levels and enhances lifespan via down regulation of its target gene, 1/October/2018, 12.02 am

Introduction: What they say  A study from Institute for Cell Biology, University of Bonn, Ulrich-Haberland Str.  Bonn, Germany; and Institute for Genetics and CECAD Research Center, […]
September 27, 2018

Repurposing the lipid-lowering drug Pitavastatin into a longevity-promoting drug: Statin-based combinatorial therapy for Lifespan extension: A therapeutic mix encompassing Pitavastatin, Ursolic acid, Maresin, DIM, Ursolic acid  Lutein, Maresin, Cholecalciferol, Catalpol, Isoliquiritigenin (PUMDULMCCI) activates autophagy, promotes leanness, increases insulin sensitivity, improves motor function, alleviates ageing feature and extends lifespan via upregulation of its target gene ATG5 (Autophagy-related 5), 27/September/2018, 7.54 pm

Introduction: What they say A study from the Global Research Laboratory, Seoul National University, Korea shows that “Overexpression of Atg5 in mice activates autophagy and extends lifespan.” This study was […]
September 26, 2018

Repurposing the lipid-lowering statin Simvastatin as a longevity-promoting agent: Statin-based combinatorial therapy for Lifespan extension: A therapeutic mix encompassing Simvastatin, Ursolic acid, Maresin, DIM, Ursolic acid  Lutein, Maresin, Cholecalciferol, Catalpol, Isoliquiritigenin (SUMDULMCCI) activates autophagy, promotes leanness, increases insulin sensitivity, improves motor function, alleviates ageing feature and extends lifespan via upregulation of its target gene ATG5 (Autophagy-related 5), 26/September/2018, 11.41 pm

Introduction: What they say A study from the Global Research Laboratory, Seoul National University, Korea shows that “Overexpression of Atg5 in mice activates autophagy and extends lifespan.” This study was […]