Longevity

October 28, 2018

Repurposing the anti-pulmonary hypertensive drug into a longevity-promoting drug: Sitaxentan (trade name: Thelin), an anti-pulmonary hypertensive drug, increases NMN/NAD levels, decreases interaction of DBC1 with PARP1, increases PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer, and aging, via down-regulation of its target gene, 28/October/2018, 1.55 pm

Introduction: What they say A study from Department of Genetics, Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA, USA; and […]
October 26, 2018

Repurposing the anti-inflammatory drug into a longevity-promoting drug: Sulindac, a nonsteroidal anti-inflammatory drug (NSAID), inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian lifespan, via upregulation of its target genes, 26/September/2018, 11.59 pm

What they say: A study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal […]
October 26, 2018

Repurposing the anti-pulmonary hypertensive drug into a longevity-promoting drug: Ambrisentan(trade name: Letairis, Volibris, Pulmonext), an anti-pulmonary hypertensive drug, increases NMN/NAD levels, decreases interaction of DBC1 with PARP1, increases PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer, and aging, via down-regulation of its target gene, 26/October/2018, 11.28 pm

Introduction: What they say A study from Department of Genetics, Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA, USA; and […]
October 26, 2018

Lengthening the lifespan of mighty humans with tiny probiotics: Probiotic Lactobacillus Salivarius LA307-based lifespan extension therapy: Lactobacillus Salivarius LA307 inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian lifespan, via upregulation of its target genes, 26/September/2018, 7.34 am

What they say: A study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal […]