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Muscle dystrophy

August 29, 2018

Reasanz(oning) to rescue muscle atrophy and wasting: Serelaxin (trade name: Reasanz),  a recombinant relaxin-2 used in the treatment of acute heart failure,  increases the expression of FGF19 and its receptor ß-Klotho, phosphorylates ERK1/2 and S6K1, decreases the expression of tumor suppressors  genes, promotes regeneration of muscle cells and hypertrophy of skeletal muscle, and reverses muscular atrophy and wasting via upregulation of its target gene, 29/August/2018, 12.01 am

Introduction: What they say A study from Department of Biology, University of Bergen, Bergen, Norway; and Univ-Lyon, CarMeN Laboratory, INSERM 1060, INRA 1397, Université Claude Bernard […]
July 29, 2018

Flu vaccine for muscle atrophy and wasting (Are you fooling us? Not really, that is what the scientific evidence says!): Influenza A(H1N1)/flu vaccine  increases the expression of FGF19 and its receptor ß-Klotho, phosphorylates ERK1/2 and S6K1, decreases the expression of tumor suppressors  genes, promotes regeneration of muscle cells and hypertrophy of skeletal muscle, and reverses muscular atrophy and wasting via upregulation of its target gene, 29/July/2018, 11.18 pm

Introduction: What they say A study from Department of Biology, University of Bergen, Bergen, Norway; and Univ-Lyon, CarMeN Laboratory, INSERM 1060, INRA 1397, Université Claude Bernard […]
June 23, 2018

Carbon monoxide-based therapy for regenerative muscle atrophy: COR-M2(Carbon monoxide (CO)- releasing molecule-2) increases the expression of IGF-1, PI3K(p85a) and B-Myb, decreases the expression of tumor suppressors, promotes regeneration of muscle cells, and reverses muscle atrophy via up regulation of its target gene, 23/June/2018, 6.23 pm

Introduction: What they say A study from the Cardiac Regeneration and Ageing Lab, School of Life Science, Shanghai University, Shanghai 200444, China shows that “miR-29b contributes […]
June 22, 2018

Unearthing an unknown function of a  known drug in regenerative muscle atrophy: Simvastatin(brand name: zocor), a lipid-lowering medication, increases the expression of IGF-1, PI3K(p85a) and B-Myb, decreases the expression of tumor suppressors, promotes regeneration of muscle cells, and reverses muscle atrophy via up regulation of its target gene, 22/February/2018, 3.04 pm

Introduction: What they say A study from the Cardiac Regeneration and Ageing Lab, School of Life Science, Shanghai University, Shanghai 200444, China shows that “miR-29b contributes […]