Reasanz(oning) to rescue muscle atrophy and wasting: Serelaxin (trade name: Reasanz),  a recombinant relaxin-2 used in the treatment of acute heart failure,  increases the expression of FGF19 and its receptor ß-Klotho, phosphorylates ERK1/2 and S6K1, decreases the expression of tumor suppressors  genes, promotes regeneration of muscle cells and hypertrophy of skeletal muscle, and reverses muscular atrophy and wasting via upregulation of its target gene, 29/August/2018, 12.01 am