Muscle dystrophy

Unearthing an unknown function of a  known drug in regenerative muscle atrophy: Simvastatin(brand name: zocor), a lipid-lowering medication, increases the expression of IGF-1, PI3K(p85a) and B-Myb, decreases the expression of tumor suppressors, promotes regeneration of muscle cells, and reverses muscle atrophy via up regulation of its target gene, 22/February/2018, 3.04 pm
Unearthing an unknown function of a  known drug in regenerative muscle atrophy: Simvastatin(brand name: zocor), a lipid-lowering medication, increases the expression of IGF-1, PI3K(p85a) and B-Myb, decreases the expression of tumor suppressors, promotes regeneration of muscle cells, and reverses muscle atrophy via up regulation of its target gene, 22/February/2018, 3.04 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Cardiac Regeneration and Ageing Lab, School of Life Science, Shanghai University, Shanghai 200444, China shows that “miR-29b contributes to multiple types of…

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Unknown function of a known drug in the treatment of muscle atrophy and wasting: Simvastatin(brand name: Zocor),  a lipid-lowering agent,  increases the expression of FGF19 and its receptor ß-Klotho, phosphorylates ERK1/2 and S6K1, decreases the expression of tumor suppressors  genes, promotes regeneration of muscle cells and hypertrophy of skeletal muscle, and reverses muscular atrophy and wasting via up regulation of its target gene, 22/June/2018, 2.50 pm
Unknown function of a known drug in the treatment of muscle atrophy and wasting: Simvastatin(brand name: Zocor),  a lipid-lowering agent,  increases the expression of FGF19 and its receptor ß-Klotho, phosphorylates ERK1/2 and S6K1, decreases the expression of tumor suppressors  genes, promotes regeneration of muscle cells and hypertrophy of skeletal muscle, and reverses muscular atrophy and wasting via up regulation of its target gene, 22/June/2018, 2.50 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from Department of Biology, University of Bergen, Bergen, Norway; and Univ-Lyon, CarMeN Laboratory, INSERM 1060, INRA 1397, Université Claude Bernard Lyon, INSA Lyon, Oullins,…

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Amino acid-based Regenerative therapy for muscle atrophy: L-Arginine, a non-essential amino acid, increases the expression of IGF-1, PI3K(p85a) and B-Myb, decreases the expression of tumor suppressors, promotes regeneration of muscle cells, and reverses muscle atrophy via up regulation of its target gene, 25/February/2017, 11.46 pm
Amino acid-based Regenerative therapy for muscle atrophy: L-Arginine, a non-essential amino acid, increases the expression of IGF-1, PI3K(p85a) and B-Myb, decreases the expression of tumor suppressors, promotes regeneration of muscle cells, and reverses muscle atrophy via up regulation of its target gene, 25/February/2017, 11.46 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Cardiac Regeneration and Ageing Lab, School of Life Science, Shanghai University, Shanghai 200444, China shows that “miR-29b contributes to multiple types of…

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Natural product-derived therapy for muscle atrophy and wasting:Acacetin, isolated from Robinia pseudoacacia (black locust) and anoda cristata, among others,  increases the expression of FGF19 and its receptor ß-Klotho, phosphorylates ERK1/2 and S6K1, decreases the expression of tumor suppressors  genes, promotes regeneration of muscle cells and hypertrophy of skeletal muscle, and reverses muscular atrophy and wasting via up regulation of its target gene, 29/December/2017, 12.24 am
Natural product-derived therapy for muscle atrophy and wasting:Acacetin, isolated from Robinia pseudoacacia (black locust) and anoda cristata, among others,  increases the expression of FGF19 and its receptor ß-Klotho, phosphorylates ERK1/2 and S6K1, decreases the expression of tumor suppressors  genes, promotes regeneration of muscle cells and hypertrophy of skeletal muscle, and reverses muscular atrophy and wasting via up regulation of its target gene, 29/December/2017, 12.24 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from Department of Biology, University of Bergen, Bergen, Norway; and Univ-Lyon, CarMeN Laboratory, INSERM 1060, INRA 1397, Université Claude Bernard Lyon, INSA Lyon, Oullins,…

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Molecular therapy for Cardiomyopathy: A pharmacological mixture encompassing Cilostazol and Aripiprazole decreases the expression of Sox6, restores the balance between slow- and fast-twitch myofiber proteins and alleviates Cardiomyopathy via up regulation of its target gene, 2/December/2017,  12.07 am
Molecular therapy for Cardiomyopathy: A pharmacological mixture encompassing Cilostazol and Aripiprazole decreases the expression of Sox6, restores the balance between slow- and fast-twitch myofiber proteins and alleviates Cardiomyopathy via up regulation of its target gene, 2/December/2017,  12.07 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say   A study from the Department of Cardiology, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, USA; and Harvard Stem Cell Institute, Harvard University, Cambridge, Massachusetts, USA shows that “Trbp regulates heart function through microRNA-mediated Sox6 repression.” This…

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Regenerative therapy for muscle atrophy: Cilostazol, a phosphodiesterase inhibitor used in the treatment of Peripheral vascular disease, increases the expression of IGF-1, PI3K(p85a) and B-Myb, decreases the expression of tumor suppressors, promotes regeneration of muscle cells, and reverses muscle atrophy via up regulation of its target gene, 1/November/2017, 11.58 pm
Regenerative therapy for muscle atrophy: Cilostazol, a phosphodiesterase inhibitor used in the treatment of Peripheral vascular disease, increases the expression of IGF-1, PI3K(p85a) and B-Myb, decreases the expression of tumor suppressors, promotes regeneration of muscle cells, and reverses muscle atrophy via up regulation of its target gene, 1/November/2017, 11.58 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Cardiac Regeneration and Ageing Lab, School of Life Science, Shanghai University, Shanghai 200444, China shows that “miR-29b contributes to multiple types of…

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