Myocardial infarction

December 1, 2020

LNCRNA-based regenerative cardiovascular therapy: LncRNA SNGH1 (small nucleolar RNA host gene) inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte proliferation, regeneration, and survival after myocardial infarction, via up-regulation of its target gene, 1/December/2020, 12.55 pm

LNCRNA-based regenerative cardiovascular therapy: LncRNA SNGH1 (small nucleolar RNA host gene) inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte proliferation, regeneration, and survival after myocardial infarction, via up-regulation of its target gene, 1/December/2020, 12.55 pm https://genomediscovery.org/wp-content/uploads/2020/12/Lnc-RNA-SNGH1-prevents-cardiomyocyte-dysfunction-and-cardiac-ageing-through-up-regulation-of-PNUTS-1-1.jpg 960 720 https://genomediscovery.org/wp-content/uploads/2020/12/Lnc-RNA-SNGH1-prevents-cardiomyocyte-dysfunction-and-cardiac-ageing-through-up-regulation-of-PNUTS-1-1.jpg December 1, 2020 December 1, 2020

What they say: A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published, in the 7 March 2013 issue of the journal Nature, by Profs. Stefanie Dimmeler…

December 17, 2019

Sauna (heat/thermal) therapy may safeguard your heart against cardiac dysfunction: Sauna (heat/thermal) therapy for cardiomyocyte proliferation and heart regeneration: Sauna (heat/thermal) therapy (at 41°C for 20 minutes) decreases tumor suppressor Mir-128 and cyclin-dependent kinase inhibitor p27 expression, increases SUZ12 expression, increases Cyclin E and CDK2 expression, promotes proliferation/re-entry of postnatal/adult cardiomyocytes, attenuates fibrosis, ameliorates cardiac dysfunction, and promotes heart repair in response to myocardial infarction, via up-regulation of its target gene, 17/December/2019, 7.14 am

Sauna (heat/thermal) therapy may safeguard your heart against cardiac dysfunction: Sauna (heat/thermal) therapy for cardiomyocyte proliferation and heart regeneration: Sauna (heat/thermal) therapy (at 41°C for 20 minutes) decreases tumor suppressor Mir-128 and cyclin-dependent kinase inhibitor p27 expression, increases SUZ12 expression, increases Cyclin E and CDK2 expression, promotes proliferation/re-entry of postnatal/adult cardiomyocytes, attenuates fibrosis, ameliorates cardiac dysfunction, and promotes heart repair in response to myocardial infarction, via up-regulation of its target gene, 17/December/2019, 7.14 am https://genomediscovery.org/wp-content/uploads/2019/12/Sauna-therapy-Promotes-cardiac-proliferation-and-regeneration-via-miR-128.jpg3_.jpg 960 720 https://genomediscovery.org/wp-content/uploads/2019/12/Sauna-therapy-Promotes-cardiac-proliferation-and-regeneration-via-miR-128.jpg3_.jpg December 17, 2019 December 17, 2019

Introduction: What they say: A recent study from Department of Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, 45267, USA; Key Laboratory of Molecular Target and…

October 17, 2019

Molecular mechanistic insights into how Prasugrel attenuates pathogenesis-associated with Myocardial infarction and protects against myocardial dysfunction: Prasugrel (Trade name: Effient, Efient), a drug used to prevent blood clots, decreases IRF3, GM-CSF (Granulocyte-macrophage colony-stimulating factor) and GRK2(G protein-coupled receptor kinase) expression, inhibits undue leukocyte activation and invasion, suppresses recruitment of inflammatory cells, inhibits ventricular dilation, and promotes heart repair and survival, via up regulation of its target genes, 17/October/2019, 11.29 pm

Molecular mechanistic insights into how Prasugrel attenuates pathogenesis-associated with Myocardial infarction and protects against myocardial dysfunction: Prasugrel (Trade name: Effient, Efient), a drug used to prevent blood clots, decreases IRF3, GM-CSF (Granulocyte-macrophage colony-stimulating factor) and GRK2(G protein-coupled receptor kinase) expression, inhibits undue leukocyte activation and invasion, suppresses recruitment of inflammatory cells, inhibits ventricular dilation, and promotes heart repair and survival, via up regulation of its target genes, 17/October/2019, 11.29 pm https://genomediscovery.org/wp-content/uploads/2019/10/Prasugrel-attenuates-pathogenesis-associated-with-myocardial-infarction4.jpg 960 720 https://genomediscovery.org/wp-content/uploads/2019/10/Prasugrel-attenuates-pathogenesis-associated-with-myocardial-infarction4.jpg October 17, 2019 October 18, 2019

Introduction: What they say: A recent study from Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, USA; and Cardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, Boston,…

July 6, 2019

Little RNA can save you from cardiac hypertrophy and fibrosis: Intracardiac injection of LncRNA Mirt2 protects against cardiac hypertrophy and fibrosis: Intracardiac injection of LncRNA Mirt2 (Long non-coding RNA myocardial infarction associated transcript 2) decreases MiR-29 expression, activates wnt- signaling and its components GSK3B, ICAT/CTNNBIP1, HBP1, and GLIS2, attenuates pathologic hypertrophy, inhibits fibrosis of the heart tissue, and improves cardiac function, via upregulation of its target gene, 6/July/2019, 11.14 pm

Little RNA can save you from cardiac hypertrophy and fibrosis: Intracardiac injection of LncRNA Mirt2 protects against cardiac hypertrophy and fibrosis: Intracardiac injection of LncRNA Mirt2 (Long non-coding RNA myocardial infarction associated transcript 2) decreases MiR-29 expression, activates wnt- signaling and its components GSK3B, ICAT/CTNNBIP1, HBP1, and GLIS2, attenuates pathologic hypertrophy, inhibits fibrosis of the heart tissue, and improves cardiac function, via upregulation of its target gene, 6/July/2019, 11.14 pm https://genomediscovery.org/wp-content/uploads/2019/07/LncRNA-Mirt2-attenuates-pathogenesis-associated-with-cardiac-hypertrophy-and-fibrosis-through-down-regulation-of-MiR29-3.jpg 960 720 https://genomediscovery.org/wp-content/uploads/2019/07/LncRNA-Mirt2-attenuates-pathogenesis-associated-with-cardiac-hypertrophy-and-fibrosis-through-down-regulation-of-MiR29-3.jpg July 6, 2019 July 6, 2019

Introduction: What they say: A recent study from the Institute of Pharmacology and Toxicology, Technical University Munich (TUM), 80802, Munich, Germany; DZHK (German Center for Cardiovascular Research), partner site Munich…

July 6, 2019

Ribonucleic acid-based therapy protects against and promotes functional recovery after Myocardial Infarction: LncRNA Mirt2 inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction, via up-regulation of its target gene, 6/July/2019, 10.41 pm

Ribonucleic acid-based therapy protects against and promotes functional recovery after Myocardial Infarction: LncRNA Mirt2 inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction, via up-regulation of its target gene, 6/July/2019, 10.41 pm https://genomediscovery.org/wp-content/uploads/2019/07/LncRNA-Mirt2-attenuates-pathogenesis-associated-with-myocardial-infarction-through-down-regulation-of-MiR34.jpg 960 720 https://genomediscovery.org/wp-content/uploads/2019/07/LncRNA-Mirt2-attenuates-pathogenesis-associated-with-myocardial-infarction-through-down-regulation-of-MiR34.jpg July 6, 2019 July 6, 2019

What they say: A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published, in the 7 March 2013 issue of of the journal Nature, by Prof Dimmler,…

May 17, 2019

Excess consumption of coffee during pregnancy increases the chances of spontaneous abortion, stillbirth & prenatal mortality: Caffeine increases DNA damage responses, suppresses telomerase expression, attenuates telomere shortening, inhibits cardiomyocyte survival, promotes cardiomyocytes apoptosis, and promotes myocardial dysfunction, via down-regulation of PNUTS, 17/May/2019, 11.22 pm

Excess consumption of coffee during pregnancy increases the chances of spontaneous abortion, stillbirth & prenatal mortality: Caffeine increases DNA damage responses, suppresses telomerase expression, attenuates telomere shortening, inhibits cardiomyocyte survival, promotes cardiomyocytes apoptosis, and promotes myocardial dysfunction, via down-regulation of PNUTS, 17/May/2019, 11.22 pm https://genomediscovery.org/wp-content/uploads/2019/05/Prenatal-caffeine-exposure-promotes-myocardial-infarction-and-cardiac-ageing-through-down-regulation-of-PNUTS.jpg2_.jpg 960 720 https://genomediscovery.org/wp-content/uploads/2019/05/Prenatal-caffeine-exposure-promotes-myocardial-infarction-and-cardiac-ageing-through-down-regulation-of-PNUTS.jpg2_.jpg May 17, 2019 May 17, 2019

What they say: A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published, in the 7 March 2013 issue of of the journal Nature (impact…