Pain

February 17, 2018

Activation of the PD-1 pathway for Pain therapy: Duloxetine (brand name: Cymbalta) increases the expression of PD-L1, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 17/February/2017, 11.34 pm

Introduction:What they say: A recent study, from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain […]
February 10, 2018

Activation of the PD-1 pathway for Pain therapy: D-3-Hydroxybutyrate (D3HB) increases the expression of PD-L1, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 10/February/2017, 8.00 pm

Introduction:What they say: A recent study, from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain […]
January 31, 2018

Activation of the PD-1 pathway for Pain therapy: Paroxetine, an antidepressant drug,  increases the expression of PD-L1, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 31/January/2017, 11.29 pm

Introduction:What they say: A recent study, from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain […]
January 17, 2018

Activation of the PD-1 pathway for Pain therapy: Sildenafil [Phosphodiesterase-5 inhibitor], a drug used in the treatment of erectile dysfunction and pulmonary arterial hypertension,  increases the expression of PD-L1, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 17/January/2017, 1.29 pm

Introduction:What they say: A recent study, from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain […]