Pain

October 2, 2017

Natural product-derived PD-1 pathway activation for Pain therapy: Emodin, isolated from Rhubarb and Polygonum multiflorum,  among others, increases the expression of PD-L1, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 02/October/2017, 11.41  pm

On the eve of Mahatma Gandhi Birth Anniversary ********* We wish everyone a happy Mahatma Gandhi Jayanti 2017. On this special occasion, we are happy to announce that Ideas posted today (02/October/2017) will […]
September 21, 2017

PD-1 pathway activation for Pain therapy: Fluoxetine, the widely used drug in the treatment of depression, mood disorders among others,  increases the expression of PD-L1, attenuates acutes and chronic pain, suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gen, 21/September/2017, 10.30  pm

Introduction:What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain […]
September 5, 2017

The PD-1 pathway activation for Pain therapy: Rivaroxaban, an anti-coagulant and a blood thinner,  increases the expression of PD-L1, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 6/september/2017, 12.28 am

Teacher’s day special ********* We wish everyone a happy Teacher’s day. On this special occasion, we are happy to announce that ideas posted today (05/September/2017) will be available to […]
August 7, 2017

Natural product-derived PD-1 pathway activation for Pain therapy: Pyrroloquinoline quinone (PQQ), isolated from Kiwisfruits, increases the expression of PD-L1, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 8/August/2017, 12.57 am

Introduction:What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain […]