Pain

April 6, 2019

Mechanistic insights into how Calcitonin gene-related peptide (CGRP) causes migraine and headache:  CGRP, a vasoactive peptide known to play a role in the pathophysiology of migraine, decreases the expression of PD-L1, aggravates acute and chronic pain, increases mechanical and thermal hypersensitivity and promotes nociceptive neuron excitability, via down-regulation of its target gene, 6/April/2019, 1.13 pm

Introduction: What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for […]
April 5, 2019

Mechanistic insights into how Opioids function as pain medication:  Endorphin-2, an endogenous opioid, increases the expression of PD-L1, attenuates acute and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability, via up-regulation of its target gene, 5/April/2019, 10.58 pm

Introduction: What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for […]
March 12, 2019

Ribonucleic acid-based pain medication therapy: LncRNA TUSC7 increases the expression of PD-L1, attenuates acute and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability, via up-regulation of its target gene, 12/March/2018, 8.49 am

Introduction: What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for […]
March 10, 2019

Ribonucleic acid-based pain medication therapy:  LncRNA NEAT1 increases the expression of PD-L1, attenuates acute and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability, via up-regulation of its target gene, 10/March/2019, 12.45 pm

Introduction: What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for […]