This year’s Noble prize winner for Physiology or Medicine Prof. Sudhof C Thomas (from Stanford University, California, USA) has published a paper in the Journal Neuron stating that “Rapid single-step induction of Functional neurons from Human pluripotent stem cells.” This study suggests that “Neurogenin-2 overexpression rapidly transforms ESCs and iPSCs into neurons.”
In connection with this finding, Dr Boominathan, Founder Director-cum-chief scientist of GBMD, reports that: Drosha inhibits the induction of functional neurons from human IPS cells. This finding suggests that targeting the expression of nuclear miRNA-processing enzyme, Drosha, in iPScs and ESCs may aid the generation of functional neurons.
Idea Proposed by: Dr L Boominathan Ph.D.
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To cite: Boominathan, The Follow-up of Noble laureates’s (Sudhof C Thomas) favorite work: Drosha inhibits the induction of functional neurons from human IPSCs and ESCs, 24/October/2013, 6.33 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
* Research cooperation