Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/
Citation: Boominathan, Insights into physiological mechanisms that inhibit the development of hyperglycemia and T2D: p63 increases CyclinD1 expression and inhibits gluconeogenesis via transcriptional regulation of Peroxisome proliferator-activated receptor γ coactivator-1α, 18/September/2014, 5.25 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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Significance: This study suggests that p63, by regulating the expression of Peroxisome proliferator-activated receptor γ coactivator-1α, it may inhibit gluconeogenesis. Thus, pharmacological formulations encompassing “p63 activators” may be used to treat DM.
* Research cooperation