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Idea Proposed/Formulated byDr L Boominathan Ph.D.

Web: http://genomediscovery.org

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Significance: This study suggests, for the first time, that Roquin, by down regulation of its target gene, it may increase the expression of metastasis suppressor TPM1.  Thus, pharmacological formulations containing “Roquin activators” can be used in the treatment of human cancers.

To citeBoominathan,   Molecular therapy for Human Cancer: Roquin [RING finger and CCCH-type zinc finger domain-containing protein 1] increases the expression of  metastasis suppressor TPM1 via down regulation of its target gene, 7/March/2015, 19.01,  Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

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* Research cooperation

Undisclosed information: How Roquin increases the expression of TPM1

Amount: $300*

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