Natural product Life-extension therapy: Neem leaf extract inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span via upregulation of its target genes, 6/October/2016, 8.40 am

Natural product Life-extension therapy: Neem leaf extract inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span via upregulation of its target genes, 6/October/2016, 8.40 am

Natural product Life-extension therapy: Neem leaf extract inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span via upregulation of its target genes, 6/October/2016, 8.40 am 150 150 Dr Boomi's Genom-2-Discovery Center

A recent study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal protein S6 kinase 1 signaling regulates mammalian life span.” This study was published in the 2 October 2009 issue of the Journal “Science” (I.F: 31.477 ) by Prof Dominic J. Withers, Dr. Selman C and others.

On the foundation of this interesting finding, Dr L Boominathan PhD, Director-cum-chief Scientist of GBMDreports, for the first time, that: Natural product Life-extension therapy: Neem leaf extract inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span via upregulation of its target genes

Idea Proposed/Formulated byDr L Boominathan Ph.D.

Neem leaf extract promotes longevity via down regulation of p70 S6 kinase

Neem leaf extract promotes longevity via down regulation of p70 S6 kinase

Significance: This study suggests a natural product-based life extension therapy. Neem leaf extract, by increasing the expression of its target gene, it may decrease the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase). Thereby,  it may promote (1) resistance to bone, immune, and motor dysfunction; (2) insulin sensitivity; and (3) longevity.  

Thus, pharmacological formulations encompassing Neem leaf extract or an active compound isolated from it can be used to extend the lifespan of an individual.

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CitationBoominathan, Natural product Life-extension therapy: Neem leaf extract inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span via upregulation of its target genes, 6/October/2016, 8.40 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

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Amount: $300

Undisclosed information: How Neem leaf extract increases mammalian life span

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