A sweet way to say no to weight gain and Diabetes: Sugar-based therapy for body weight control, energy homeostasis and TIIDM: D-Mannose, a C-2 epimer of glucose, decreases CADM1 and its downstream target genes that inhibit glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 18/March/2017, 9.53 am