Research findings to Therapeutic opportunity:
The study presented here suggests that MiRNA-9600, by decreasing the expression of its target genes, it may increase the expression of Matrix metalloproteinases inhibitor TIMP3. Thereby, it may inhibit prevent the degradation of extracellular matrix, migration, invasion and metastasis of cancer cells. Thus, pharmacological formulations encompassing “MiRNA-9600 activators” may be used to inhibit the progression of invasive tumors.
Details of the research findings:
Idea Proposed/Formulated (with experimental evidence) by:
Dr L Boominathan Ph.D.
Undisclosed information: How MiRNA-9600 increases the expression of metastasis suppressor TIMP3
Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/
References:
Citation: Boominathan, L., Anti-metastasis therapy: MiRNA-9600 increases the expression of Metastasis suppressor TIMP3 (TIMP Metallopeptidase Inhibitor 3) and inhibits migration, invasion and metastasis of cancer cells via down regulation of its target gene, 20/November/2015, 9.09 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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