Research findings to Therapeutic opportunity:
The study presented here suggests that MiRNA-9600, by increasing the expression of its target genes, it may decrease the expression of KLF4.
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Thereby, it may inhibit proliferation, and promote apoptosis of cancer cells. Thus, pharmacological formulations encompassing “MiRNA-9600 activators” may be used to inhibit cancer progression.
Details of the research findings:
Idea Proposed/Formulated (with experimental evidence) by:
Dr L Boominathan Ph.D.
Undisclosed mechanistic information: How does MiRNA-9600 decrease the expression of KLF4?
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References:
Citation: Boominathan, L., Anticancer therapy targeting the cancer stem cells: MiRNA-9600 decreases the expression of KLF4, suppresses proliferation, and promotes apoptosis of cancer cells via down regulation of its target gene, 24/January/2017, 10.49 pm, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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