Diabetes

A sweet way to say no to Diabetes: Sugar-based therapy for TIIDM: Raffinose, a trisaccharide isolated from cotton seed flour,  increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state, via up-regulation of  its target gene Lin28, 14/April/2018, 6.04 am
A sweet way to say no to Diabetes: Sugar-based therapy for TIIDM: Raffinose, a trisaccharide isolated from cotton seed flour,  increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state, via up-regulation of  its target gene Lin28, 14/April/2018, 6.04 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say:   A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows that “The Lin28/let-7 axis regulates glucose metabolism.” This study…

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Bonding your way to decrease blood pressure/sugar and extend lifespan: Oxytocin-based Lifespan and healthspan extension therapy: Oxytocin,  a peptide hormone and neuropeptide known to play a role in empathy, generosity, child birth and so on, decreases blood sugar and blood pressure levels and prolongs mammalian life span, via down regulation of angiotensin II type I receptor (AT1R), 13/April/2018, 7.09 am
Bonding your way to decrease blood pressure/sugar and extend lifespan: Oxytocin-based Lifespan and healthspan extension therapy: Oxytocin,  a peptide hormone and neuropeptide known to play a role in empathy, generosity, child birth and so on, decreases blood sugar and blood pressure levels and prolongs mammalian life span, via down regulation of angiotensin II type I receptor (AT1R), 13/April/2018, 7.09 am 960 720 Dr Boomi's Genom-2-Discovery Center

Significance of the study: It has been shown earlier that antagonizing angiotensin II type I receptor (AT1R) expression may prolong mammalian life span. Further, it has been shown that disruption of AT1R (AGTR1)…

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Dietary fibre-based therapy for Diabetes Mellitus: Inulin (Fructans), a soluble fibre from chicory, augments the expression of FGF19 and FGF1,  attenuates hepatic glucose production, decreases hepatic acetyl CoA content, brings down the levels of plasma ACTH, and corticosterone, augments insulin sensitivity, promotes weight loss and alleviates TIDM via up regulation of its target gene, 6/April/2018, 7.55 am
Dietary fibre-based therapy for Diabetes Mellitus: Inulin (Fructans), a soluble fibre from chicory, augments the expression of FGF19 and FGF1,  attenuates hepatic glucose production, decreases hepatic acetyl CoA content, brings down the levels of plasma ACTH, and corticosterone, augments insulin sensitivity, promotes weight loss and alleviates TIDM via up regulation of its target gene, 6/April/2018, 7.55 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say  A study from Diabetes and Obesity Center of Excellence, Department of Medicine, University of Washington, Seattle, Washington, USA shows that Central injection of FGF1 induces sustained…

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A noble way to say no to Diabetes: Noble gas-based regenerative therapy for reversing diabetes:Inhalation of Xenon gas increases the expression of Sox17, Sox2, Pdx-1, and Ngn3, decreases mTOR expression, promotes regeneration of insulin-producing ß cells, increases insulin secretion, promotes glucose homeostasis and reverses T1D and T2D via down regulation of its target gene, 5/April/2018, 1.24 am
A noble way to say no to Diabetes: Noble gas-based regenerative therapy for reversing diabetes:Inhalation of Xenon gas increases the expression of Sox17, Sox2, Pdx-1, and Ngn3, decreases mTOR expression, promotes regeneration of insulin-producing ß cells, increases insulin secretion, promotes glucose homeostasis and reverses T1D and T2D via down regulation of its target gene, 5/April/2018, 1.24 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Longevity Institute, School of Gerontology, Department of Biological Sciences, University of Southern California, 3715 McClintock Avenue, Los Angeles, California, USA; and Koch Institute…

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A sweet way to say no to metabolic disease: Sugar-based therapy for TIIDM and obesity-associated metabolic deficits: D-Mannose, a C-2 epimer of Glucose,, increases Lipocalin 2 (LCN2) expression, activates an MC4R-dependent anorexigenic pathway, suppresses appetite and weight gain, increases insulin secretion, improves glucose tolerance, promotes glucose homeostasis, improves obesity-associated metabolic deficits and prevents progression to TIIDM via down regulation of its target gene, 5/April/2018, 1.05 am
A sweet way to say no to metabolic disease: Sugar-based therapy for TIIDM and obesity-associated metabolic deficits: D-Mannose, a C-2 epimer of Glucose,, increases Lipocalin 2 (LCN2) expression, activates an MC4R-dependent anorexigenic pathway, suppresses appetite and weight gain, increases insulin secretion, improves glucose tolerance, promotes glucose homeostasis, improves obesity-associated metabolic deficits and prevents progression to TIIDM via down regulation of its target gene, 5/April/2018, 1.05 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Department of Physiology-Cellular Biophysics, College of Physicians and Surgeons, Columbia University, New York, New York, USA shows that “MC4R-dependent suppression of appetite by…

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Dietary fibre-based therapy for body weight control, energy homeostasis and TIIDM: Inulin (fructans),  a polysaccharide isolated from chicory, inhibits DNA methyltransferase 3a (Dnmt3a) expression, increases FGF21 expression, augments insulin sensitivity, increases glucose tolerance, and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 5/April/2018, 12.51 am
Dietary fibre-based therapy for body weight control, energy homeostasis and TIIDM: Inulin (fructans),  a polysaccharide isolated from chicory, inhibits DNA methyltransferase 3a (Dnmt3a) expression, increases FGF21 expression, augments insulin sensitivity, increases glucose tolerance, and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 5/April/2018, 12.51 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say  A study from Nutritional Sciences and Toxicology Department, University of California, Berkeley, Berkeley, United States shows that “Dnmt3a is an epigenetic mediator of adipose insulin resistance.”…

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