October 5, 2018

A probiotic way to treat TIIDM and obesity-associated metabolic deficits: Probiotic Lactobaccilus gasseri SBT2055 increases Lipocalin 2 (LCN2) expression, activates an MC4R-dependent anorexigenic pathway, suppresses appetite and weight gain, increases insulin secretion, improves glucose tolerance, promotes glucose homeostasis, improves obesity-associated metabolic deficits and prevents progression to TIIDM via down-regulation of its target gene, 5/October/2018, 11.01 pm

Introduction: What they say A study from the Department of Physiology-Cellular Biophysics, College of Physicians and Surgeons, Columbia University, New York, New York, USA shows that “MC4R-dependent […]
October 5, 2018

A probiotic way to stay free of diabetes: Probiotic Lactobacillus gasseri-based therapy for body weight control, energy homeostasis and TIIDM: Probiotic Lactobacillus gasseri inhibits DNA methyltransferase 3a (Dnmt3a) expression, increases FGF21 expression, augments insulin sensitivity, increases glucose tolerance, and protects from diet-induced obesity and TIIDM, via up-regulation of its target gene, 5/September/2018, 10.46 pm

Introduction: What they say  A study from Nutritional Sciences and Toxicology Department, University of California, Berkeley, Berkeley, United States shows that “Dnmt3a is an epigenetic mediator […]
October 2, 2018

Nicotine-based therapy for autoimmune diabetes (TIDM): Nicotine, the major components of cigarettes, increases PD-L1 expression, increases Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up regulation of its target gene, 2/October/2018, 11.26 pm

On the eve of Mahatma Gandhi Birth Anniversary We wish everyone a happy Mahatma Gandhi Jayanti 2018. On this special occasion, we are happy to announce that Ideas posted today (02/October/2018) will be […]
September 26, 2018

Mechanistic insights into how a statin-based drug stifles anxiety and depression: Simvastatin, a lipid-lowering agent, decreases PHF8 levels, increases the expression of serotonin receptors Htr1a and Htr2a, and promotes resistance to stress-induced -anxiety and -depression, via down-regulation of its target gene, 26/September/2018, 11.22 pm

Introduction: What they say:  A study from Department of Molecular Biology, Cancer Center and Center for Regenerative Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA; Department […]