Hypertension

January 20, 2018

Molecular therapy for pulmonary arterial hypertension: Tadalafil [Brand name: Cialis, Adcirca and others], a cGMP-specific phosphodiestrase type 5 inhibitor used in the treatment of erectile dysfunction and pulmonary arterial hypertension, inhibits the development of pulmonary arterial hypertension via down regulation of its target gene Notch3, 20/January/2018, 11.33 pm

What they say:  A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published, in the 15 November  2009 issue of the journal “Nature Medicine”[the number […]
January 17, 2018

Molecular therapy for pulmonary arterial hypertension: Sildenafil [Brand name: Revatio, Viagra and others], a cGMP-specific phosphodiestrase type 5 inhibitor used in the treatment of erectile dysfunction and pulmonary hypertension, inhibits the development of pulmonary arterial hypertension via down regulation of its target gene Notch3, 17/January/2018, 9.28 am

What they say:  A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published, in the 15 November  2009 issue of the journal “Nature Medicine”[the number […]
January 8, 2018

Molecular therapy for blood-stage Plasmodium infection:  Amiloride (trade name Midamor), an anti-hypertensive drug, decreases the expression of CTLA-4, PD-L1 and LAG-3, promotes CD4+ T-cell function, increases secretion of protective antibodies, promotes and clear blood-stage malaria via up regulation of its target gene, 8/January/2017, 10.12 pm

Introduction: What they say A study from the Department of Microbiology and Immunology, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA shows that […]
January 1, 2018

Natural product therapy for pulmonary arterial hypertension: α-Linoleic acid, isolated from Flax seeds, inhibits the development of pulmonary arterial hypertension via down regulation of its target gene Notch3, 1/January/2018, 5.41 am

What they say:  A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published, in the 15 November  2009 issue of the journal “Nature Medicine”[the […]