Ideas

Urine-derived compound functions as a longevity promoter: Ulinastatin (trade name: Miraclid, Ulinase, U-Tryp,Bikunin and Urinastatin), a trypsin inhibitor found in human urine and used in the treatment of  acute/chronic pancreatitis, burns and others, slows down cardiac aging, and increases lifespan, via up-regulation of BubR1 and others genes, 16/January/2019, 12.51 am
Urine-derived compound functions as a longevity promoter: Ulinastatin (trade name: Miraclid, Ulinase, U-Tryp,Bikunin and Urinastatin), a trypsin inhibitor found in human urine and used in the treatment of  acute/chronic pancreatitis, burns and others, slows down cardiac aging, and increases lifespan, via up-regulation of BubR1 and others genes, 16/January/2019, 12.51 am 960 720 Dr Boomi's Genom-2-Discovery Center

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston, USA; and Department of Pharmacology,…

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RNA-based therapy for aging-associated diseases and Lifespan extension: LncRNA PRLB  inhibits the interaction of DBC1 with PARP1, increases the PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer and aging, via down-regulation of its target gene, 15/January/2019, 11.58 pm
RNA-based therapy for aging-associated diseases and Lifespan extension: LncRNA PRLB  inhibits the interaction of DBC1 with PARP1, increases the PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer and aging, via down-regulation of its target gene, 15/January/2019, 11.58 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from Department of Genetics, Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA, USA; and Department of Pharmacology, School…

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Natural product-based anti-ageing and Lifespan extension therapy:  A pharmaceutical mixture encompassing Celecoxib and quercetin (CQ) increases CHIP levels, increases monoubiquitylation of insulin receptor (INSR), decreases INSR protein levels and enhances lifespan, via down regulation of its target gene, 15/January/2019, 11.47 pm
Natural product-based anti-ageing and Lifespan extension therapy:  A pharmaceutical mixture encompassing Celecoxib and quercetin (CQ) increases CHIP levels, increases monoubiquitylation of insulin receptor (INSR), decreases INSR protein levels and enhances lifespan, via down regulation of its target gene, 15/January/2019, 11.47 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say  A study from Institute for Cell Biology, University of Bonn, Ulrich-Haberland Str.  Bonn, Germany; and Institute for Genetics and CECAD Research Center, University of Cologne, Joseph-Stelzmann…

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Molecular therapy for glaucoma: Ulinastatin (trade name: Miraclid, Ulinase, U-Tryp,Bikunin and Urinastatin), an urinary trypsin inhibitor used in the treatment of  acute/chronic pancreatitis, burns and others,  increases Nmnat1 expression, increases NAD+ levels, improves neuronal dysfunction, and protects against glaucoma,  via down regulation of its target gene, 15/January/2018, 11.36 pm
Molecular therapy for glaucoma: Ulinastatin (trade name: Miraclid, Ulinase, U-Tryp,Bikunin and Urinastatin), an urinary trypsin inhibitor used in the treatment of  acute/chronic pancreatitis, burns and others,  increases Nmnat1 expression, increases NAD+ levels, improves neuronal dysfunction, and protects against glaucoma,  via down regulation of its target gene, 15/January/2018, 11.36 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the The Jackson Laboratory, Bar Harbor, ME 04609, USA; Department of Ophthalmology, Tufts University of Medicine, Boston, MA 02111, USA; The Howard Hughes…

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Ribonucleic acid-based therapy for Myocardial Infarction: LncRNA 015192 inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction, via up-regulation of PNUTS, 16/January/2019, 1.00 pm
Ribonucleic acid-based therapy for Myocardial Infarction: LncRNA 015192 inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction, via up-regulation of PNUTS, 16/January/2019, 1.00 pm 960 720 Dr Boomi's Genom-2-Discovery Center

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published, in the 7 March  2013 issue of of the journal Nature,  by Prof Dimmler,…

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Molecular therapy for diabetes: Estrogen receptor-β (ER-β)  increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state, via up-regulation of  its target gene Lin28, 15/January/2019, 11.01 pm
Molecular therapy for diabetes: Estrogen receptor-β (ER-β)  increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state, via up-regulation of  its target gene Lin28, 15/January/2019, 11.01 pm 960 720 Dr Boomi's Genom-2-Discovery Center

 Introduction: What they say:   A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows that “The Lin28/let-7 axis regulates glucose metabolism.” This study…

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