Ideas

February 3, 2019
Published by admin_auro at February 3, 2019
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Combinatorial therapy for glioblastoma: A therapeutic mix encompassing Metformin and Navitoclax (ABT-263) [MAN] inhibits the expression of JMJD6, impairs functioning of transcription elongation machinery, inhibits the proliferation of glioblastoma cells, suppresses tumor cell migration, reduces metastasis and prolongs survival via down-regulation of its target gene, 3/February/2019, 10.39 pm

Introduction: What they say:  A study from the Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Ohio, USA shows that “Transcription elongation factors […]
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February 2, 2019
Published by admin_auro at February 2, 2019
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AIRE comes to the rescue of Diabetes Mellitus: AIRE (Autoimmune regulator) augments the expression of FGF19 and FGF1,  attenuates hepatic glucose production, decreases hepatic acetyl CoA content, brings down the levels of plasma ACTH, and corticosterone, augments insulin sensitivity, promotes weight loss and alleviates TIDM via upregulation of its target gene, 2/February/2019, 6.11 pm

Introduction: What they say  A study from Diabetes and Obesity Center of Excellence, Department of Medicine, University of Washington, Seattle, Washington, USA shows that Central injection […]
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February 2, 2019
Published by admin_auro at February 2, 2019
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Molecular therapy for alleviating Diabetes: Alogliptin, an antidiabetic drug in the DPP-4 inhibitor class, increases GLP1R and Caveolin-1 (CAV-1) expression, promotes glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM, via up-regulation of its target gene, 2/February/2019, 5.54 pm

Introduction: What they say A study from the Comprehensive Diabetes Center and Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Alabama at Birmingham, […]
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February 2, 2019
Published by admin_auro at February 2, 2019
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Molecular therapy for safeguarding your heart against cardiac dysfunction: Sofalcone, a gastrointestinal medication,  decreases tumor suppressor Mir-128 and cyclin-dependent kinase inhibitor p27 expression, increases SUZ12 expression, increases Cyclin E and CDK2 expression, promotes proliferation/re-entry of postnatal/adult cardiomyocytes, attenuates fibrosis, ameliorates cardiac dysfunction, and promotes heart repair in response to myocardial infarction, via up-regulation of its target gene, 2/February/2019, 5.44 pm

Introduction: What they say: A recent study from Department of Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, 45267, USA; Key Laboratory […]
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