Ideas

Mechanistic insights into how valsartan may aid in attenuating pathogenesis-associated with Myocardial infarction: Valsartan(brand name: Diovan),  used in the treatment of high blood pressure and congestive heart failure, decreases IRF3 (Interferon regulatory transcription factor-3), GM-CSF (Granulocyte-macrophage colony-stimulating factor) and GRK2(G protein-coupled receptor kinase) expression, inhibits undue leucocyte activation and invasion, suppresses recruitment of inflammatory cells, inhibits ventricular dilation, and promotes heart repair and survival, via up-regulation of its target gene, 25/October/2018, 2.27 pm
Mechanistic insights into how valsartan may aid in attenuating pathogenesis-associated with Myocardial infarction: Valsartan(brand name: Diovan),  used in the treatment of high blood pressure and congestive heart failure, decreases IRF3 (Interferon regulatory transcription factor-3), GM-CSF (Granulocyte-macrophage colony-stimulating factor) and GRK2(G protein-coupled receptor kinase) expression, inhibits undue leucocyte activation and invasion, suppresses recruitment of inflammatory cells, inhibits ventricular dilation, and promotes heart repair and survival, via up-regulation of its target gene, 25/October/2018, 2.27 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A recent study from Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, USA; and Cardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, Boston,…

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The tiny Probiotic Bacillus subtillis B10 comes to the rescue of blood-stage Plasmodium infection: Probiotic Bacillus subtillis B10 decreases the expression of CTLA-4, PD-L1 and LAG-3, promotes CD4+ T-cell function, increases secretion of protective antibodies, promotes and clears blood-stage malaria, via up regulation of its target gene, 24/October/2018, 11.53 pm
The tiny Probiotic Bacillus subtillis B10 comes to the rescue of blood-stage Plasmodium infection: Probiotic Bacillus subtillis B10 decreases the expression of CTLA-4, PD-L1 and LAG-3, promotes CD4+ T-cell function, increases secretion of protective antibodies, promotes and clears blood-stage malaria, via up regulation of its target gene, 24/October/2018, 11.53 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Department of Microbiology and Immunology, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA shows that “Regulatory T cells impede…

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A probiotic way to decrease blood pressure/sugar and extend lifespan: Probiotic Lactobacillus gasseri SBT2055  prolongs mammalian life span via down-regulation of angiotensin II type I receptor (AT1R), 24/October/2018, 11.00 pm
A probiotic way to decrease blood pressure/sugar and extend lifespan: Probiotic Lactobacillus gasseri SBT2055  prolongs mammalian life span via down-regulation of angiotensin II type I receptor (AT1R), 24/October/2018, 11.00 pm 960 720 Dr Boomi's Genom-2-Discovery Center

The significance of the study: It has been shown earlier that antagonizing angiotensin II type I receptor (AT1R) expression may prolong mammalian life span. Further, it has been shown that disruption of AT1R…

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Anti-hypertensive drug Amlodipine for an enhanced, extended, and healthy lifespan: Amlodipine (trade name: Norvasc) increases NMN/NAD levels, decreases interaction of DBC1 with PARP1, increases PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer, and aging, via down-regulation of its target gene, 24/October/2018, 10.46 pm
Anti-hypertensive drug Amlodipine for an enhanced, extended, and healthy lifespan: Amlodipine (trade name: Norvasc) increases NMN/NAD levels, decreases interaction of DBC1 with PARP1, increases PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer, and aging, via down-regulation of its target gene, 24/October/2018, 10.46 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from Department of Genetics, Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA, USA; and Department of Pharmacology, School…

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Combating infective agents with Probiotics:  Probiotics-based adjuvant therapy for viral and bacterial infections: Probiotic Bacillus subtilis B10 inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1,  respiratory syncytial,  Sindbis, and SFV viruses by increasing the Levels of the antiviral Proteins IFITM3, & Interferon-stimulated gene, 24/October/2018, 10.31 pm
Combating infective agents with Probiotics:  Probiotics-based adjuvant therapy for viral and bacterial infections: Probiotic Bacillus subtilis B10 inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1,  respiratory syncytial,  Sindbis, and SFV viruses by increasing the Levels of the antiviral Proteins IFITM3, & Interferon-stimulated gene, 24/October/2018, 10.31 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A study from the Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard Medical School, Charlestown, MA 02129, USA shows that “The IFITM proteins…

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Taming microbial infections with anti-tapeworm drugs:  Niclosamide (trade name: Niclocide, Fenasal, Phenasal), an anti-tapeworm drug, inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1,  respiratory syncytial,  Sindbis, and SFV viruses by increasing the Levels of the antiviral Proteins IFITM3, & Interferon-stimulated gene 22/October/2018, 11.59 pm
Taming microbial infections with anti-tapeworm drugs:  Niclosamide (trade name: Niclocide, Fenasal, Phenasal), an anti-tapeworm drug, inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1,  respiratory syncytial,  Sindbis, and SFV viruses by increasing the Levels of the antiviral Proteins IFITM3, & Interferon-stimulated gene 22/October/2018, 11.59 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A study from the Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard Medical School, Charlestown, MA 02129, USA shows that “The IFITM proteins…

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