Ideas

May 23, 2019

A commonly prescribed blood-pressure drug comes to the rescue of diabetes (TIIDM): Verapamil (brand name: Calan, Isoptin, and others), a calcium channel blocker used in the treatment of high blood pressure, angina, supraventricular tachycardia, migraines, increases Pax6 and insulin expression, decreases the levels of glucagon, ghrelin and Somatostatin, reduces metabolic stress, improves insulin sensitivity, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 23/May/2019, 10.31 pm

Introduction: What they say A study from the Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, […]
May 22, 2019

Mechanistic insights into how Gabapentin attenuates neuropathic pain: Gabapentin (Brand name: Neurontin), used to treat partial seizures, neuropathic pain (caused by: diabetic neuropathy, postherpetic neuralgia and central neuropathic pain), restless legs syndrome and others, increases the expression of PD-L1, attenuates acute and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 22/May/2019, 11.41 pm

Introduction:What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain […]
May 22, 2019

Mechanistic insights into how consumption of excess amount of coffee during pregnancy may deteriorate memory, learning, and cognition of fetus in the womb:  Caffeine, one of the main components of coffee, decreases Tissue inhibitor of metalloproteinases 2 (TIMP2) and BDNF (Brain derived growth factor) levels, attenuates cognition, and aggravates age-associated decline in memory and learning, via up-regulation of its target genes, 22/May/2019, 11.14 pm

Introduction: What they say A study from Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California 94305, USA;  Paul F. Glenn Center […]
May 22, 2019

Live longer by consuming Seasame seeds or oil: Seasamin-based Lifespan extension therapy: Seasamin, a lignan derived from seasame seeds (Sesamum indicum L.),  inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian lifespan by regulating the expression of its target genes, 22/May/2019, 10.17 pm

What they say: A study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal […]
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