Ideas

January 16, 2019

Published by admin_auro at January 16, 2019

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Molecular therapy for glaucoma: Trimetazidine (TMZ), the drug used in the treatment of angina pectoris, increases Nmnat1 expression, increases NAD+ levels, improves neuronal dysfunction, and protects against glaucoma, via down regulation of its target gene, 16/January/2018, 11.27 pm

Introduction: What they say A study from the The Jackson Laboratory, Bar Harbor, ME 04609, USA; Department of Ophthalmology, Tufts University of Medicine, Boston, MA 02111, […]

January 16, 2019

Published by admin_auro at January 16, 2019

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Mechanistic insights into how Fasudil functions as a learning/memory/cognitive-enhancer: Fasudil (brand name: hydroxyfasudil), a vasodilator used in the treatment of pulmonary hypertension, stroke and others, increases Tissue inhibitor of metalloproteinases 2 (TIMP2) levels, improves cognition, and decreases age-associated decline in memory and learning, via down-regulation of its target genes, 16/January/2019, 11.18 pm

Introduction: What they say: A study from Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California 94305, USA; Paul F. Glenn Center […]

January 15, 2019

Published by admin_auro at January 15, 2019

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Urine-derived compound functions as a longevity promoter: Ulinastatin (trade name: Miraclid, Ulinase, U-Tryp,Bikunin and Urinastatin), a trypsin inhibitor found in human urine and used in the treatment of acute/chronic pancreatitis, burns and others, slows down cardiac aging, and increases lifespan, via up-regulation of BubR1 and others genes, 16/January/2019, 12.51 am

What they say: Introduction: A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston, USA; […]

January 15, 2019

Published by admin_auro at January 15, 2019

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RNA-based therapy for aging-associated diseases and Lifespan extension: LncRNA PRLB inhibits the interaction of DBC1 with PARP1, increases the PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer and aging, via down-regulation of its target gene, 15/January/2019, 11.58 pm

Introduction: What they say A study from Department of Genetics, Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA, USA; and […]