Ideas

A sweet way to extend lifespan: Sugar-based Lifespan extension therapy: D-Allulose/D-Psicose, a low-calorie sweetener isolated from natural products, may increase life span via up-regulation of its target gene BubR1, 16/March/2018, 6.50 am
A sweet way to extend lifespan: Sugar-based Lifespan extension therapy: D-Allulose/D-Psicose, a low-calorie sweetener isolated from natural products, may increase life span via up-regulation of its target gene BubR1, 16/March/2018, 6.50 am 960 720 Dr Boomi's Genom-2-Discovery Center

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and Department of Pharmacology, School…

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Natural product-based therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: Hesperidin, isolated from citrus aurantium, increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state via up-regulation of  its target gene Lin28, 16/March/2018, 6.38 am
Natural product-based therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: Hesperidin, isolated from citrus aurantium, increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state via up-regulation of  its target gene Lin28, 16/March/2018, 6.38 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say:   A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows that “The Lin28/let-7 axis regulates glucose metabolism.” This study…

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Amino acid-based therapy for Myocardial Infarction:  Tryptophan, an essential amino acid and precursor of the neurotransmitter serotonin and the sleep hormone melatonin, inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction, via up regulation of PNUTS, 16/March/2018, 6.26 am
Amino acid-based therapy for Myocardial Infarction:  Tryptophan, an essential amino acid and precursor of the neurotransmitter serotonin and the sleep hormone melatonin, inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction, via up regulation of PNUTS, 16/March/2018, 6.26 am 960 720 Dr Boomi's Genom-2-Discovery Center

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published, in the 7 March  2013 issue of of the journal Nature,  by Prof Dimmler,…

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Sugar-based therapy for Metastatic cancers: Xylobiose, a disaccharide of xylose, increases the expression of tumor/metastatic suppressors TIMP3 and CCM3/KRIT1 , inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 15/March/2017, 11,23 pm
Sugar-based therapy for Metastatic cancers: Xylobiose, a disaccharide of xylose, increases the expression of tumor/metastatic suppressors TIMP3 and CCM3/KRIT1 , inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 15/March/2017, 11,23 pm 960 720 Dr Boomi's Genom-2-Discovery Center

From Significance of the study to Public health relevance:  Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more than half of them…

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A sweetest way to control body weight, energy homeostasis and TIIDM: Phyllodulcin, a natural sweetener 400-800 times sweeter than sugar, increases REV-ERB and its down stream target genes, inhibits lipid accumulation, improves dyslipidemia and insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 15/March/2017,12.10 am
A sweetest way to control body weight, energy homeostasis and TIIDM: Phyllodulcin, a natural sweetener 400-800 times sweeter than sugar, increases REV-ERB and its down stream target genes, inhibits lipid accumulation, improves dyslipidemia and insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 15/March/2017,12.10 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Department of Molecular Therapeutics, The Scripps Research Institute, Jupiter, Florida 33458, USA shows that “Regulation of circadian behaviour and metabolism by synthetic…

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A sweet way to extend lifespan: Sugar-based Lifespan extension therapy: Rebaudioside A, a natural sweetener  that is 200 times sweeter than sugar is isolated from Stevia rebaudiana, may increase life span via up-regulation of its target gene BubR1, 14/March/2018, 11.23 pm
A sweet way to extend lifespan: Sugar-based Lifespan extension therapy: Rebaudioside A, a natural sweetener  that is 200 times sweeter than sugar is isolated from Stevia rebaudiana, may increase life span via up-regulation of its target gene BubR1, 14/March/2018, 11.23 pm 960 720 Dr Boomi's Genom-2-Discovery Center

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and Department of Pharmacology, School…

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