Ideas

Amino acid-based therapy for Myocardial Infarction:  Isoleucine, a branched-chain amino acid, inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction, via up regulation of PNUTS, 14/March/2018, 11.13 pm
Amino acid-based therapy for Myocardial Infarction:  Isoleucine, a branched-chain amino acid, inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction, via up regulation of PNUTS, 14/March/2018, 11.13 pm 960 720 Dr Boomi's Genom-2-Discovery Center

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published, in the 7 March  2013 issue of of the journal Nature,  by Prof Dimmler,…

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Regenerative therapy for improving memory in aged individuals: Hesperidin, a flavan-on glycoside isolated from citrus fruits, increases Tissue inhibitor of metalloproteinases 2 (TIMP2) levels, improves cognition, and decreases age-associated decline in memory and learning, via down regulation of its target genes, 14/March/2018, 11.01 pm
Regenerative therapy for improving memory in aged individuals: Hesperidin, a flavan-on glycoside isolated from citrus fruits, increases Tissue inhibitor of metalloproteinases 2 (TIMP2) levels, improves cognition, and decreases age-associated decline in memory and learning, via down regulation of its target genes, 14/March/2018, 11.01 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A study from Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California 94305, USA;  Paul F. Glenn Center for the Biology of…

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Amino acid-based therapy for Regenerating the lost pancreatic β-cells in Diabetic patients:Tryptophan, an essential amino acid and precursor of the neurotransmitter serotonin and the sleep hormone Melatonin, increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state via up-regulation of  its target gene Lin28, 14/March/2018, 10.53 pm
Amino acid-based therapy for Regenerating the lost pancreatic β-cells in Diabetic patients:Tryptophan, an essential amino acid and precursor of the neurotransmitter serotonin and the sleep hormone Melatonin, increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state via up-regulation of  its target gene Lin28, 14/March/2018, 10.53 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say:   A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows that “The Lin28/let-7 axis regulates glucose metabolism.” This study…

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Sugar-based therapy for Metastatic cancers: Xylobiose, a disaccharide of xylose, increases the expression of tumor/metastatic suppressors TPM1 and TAp63, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 14/March/2017, 10.43 pm
Sugar-based therapy for Metastatic cancers: Xylobiose, a disaccharide of xylose, increases the expression of tumor/metastatic suppressors TPM1 and TAp63, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 14/March/2017, 10.43 pm 960 720 Dr Boomi's Genom-2-Discovery Center

From Significance of the study to Public health relevance:  Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more than half of them…

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A sweet way to extend lifespan: Sugar-based Life-extension therapy: D-Allose, an aldohexose sugar,  inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span by regulating the expression of its target genes, 13/March/2017, 11.34 pm
A sweet way to extend lifespan: Sugar-based Life-extension therapy: D-Allose, an aldohexose sugar,  inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span by regulating the expression of its target genes, 13/March/2017, 11.34 pm 960 720 Dr Boomi's Genom-2-Discovery Center

What they say: A study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal protein S6 kinase 1…

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D-Allulose-based therapy for Myocardial Infarction:  D-Allulose (also known as D-Psicose), a fructose isomer and sweetener found in jackfruit, figs, raisins, wheat and others, inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction, via up regulation of PNUTS, 13/March/2018, 11.18 pm, 
D-Allulose-based therapy for Myocardial Infarction:  D-Allulose (also known as D-Psicose), a fructose isomer and sweetener found in jackfruit, figs, raisins, wheat and others, inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction, via up regulation of PNUTS, 13/March/2018, 11.18 pm,  960 720 Dr Boomi's Genom-2-Discovery Center

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published, in the 7 March  2013 issue of of the journal Nature,  by Prof Dimmler,…

read more
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