Ideas

September 21, 2018

Published by admin_auro at September 21, 2018

Categories

A probiotic way to lengthen lifespan: Probiotic Lactobacillus Previs increases NMN/NAD levels, decreases interaction of DBC1 with PARP1, increases PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer, and aging, via down-regulation of its target gene, 21/September/2018, 5.45 pm

Introduction: What they say A study from Department of Genetics, Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA, USA; and […]

September 21, 2018

Published by admin_auro at September 21, 2018

Categories

Ideas
NAFLD

Turning to Probiotic Lactobacillus acidophilus for lowering cholesterol, and triglycerides levels and for promoting weight loss: Repurposing the Probiotic Lactobacillus acidophilus into a cholesterol-lowering agent that inhibits Non-alcoholic fatty liver disease (NAFLD): Probiotic Lactobacillus acidophilus decreases the levels of HMGCR, triglycerides, free cholesterol, and total cholesterol and prevents the progression of Non-alcoholic fatty liver disease (NAFLD, via up-regulation of its target gene, 21/September/2018, 5.17 pm

The significance of the study: Given that: (1) 15-30% of Western populations suffer from Non-alcoholic fatty liver disease (NAFLD), while 6-25% of Asian populations suffer from it; (2) 75 […]

September 21, 2018

Published by admin_auro at September 21, 2018

Categories

A derivative of Estrone comes to the rescue of anxiety and depression: Hydroxyestrone (16αOHE), a derivative of weak female reproductive steroid hormone Estrone, decreases PHF8 levels, increases the expression of serotonin receptors Htr1a and Htr2a, and promotes resistance to stress-induced -anxiety and -depression, via down-regulation of its target gene, 21/September/2018, 4.56 am

Introduction: What they say: A study from Department of Molecular Biology, Cancer Center and Center for Regenerative Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA; Department […]

September 18, 2018

Published by admin_auro at September 18, 2018

Categories

Cancer
Ideas

Awakening the sleeping/cancer-protecting angels in mutant p53-expressing human tumors: PCGF2/Mel-18 increases the expression of tumor suppressors genes, such as SMAD7, p12DOC1/CDK2AP1, INK4a/ARF, TA-p73, TA-p63, p53, and others, induces regression of p53-mutated human tumors, via down-regulation of its target gene, 18/September/2018, 9.05 pm

From Significance of the study to Public health relevance: Given that: (1) cancer suppressor p53 is mutated in more than 50% of human cancers of different […]