Ideas – Page 245

September 16, 2018

Published by admin_auro at September 16, 2018

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Combinatorial therapy for Metastatic ovarian cancers: A therapeutic mix encompassing Despiramine, Andrographlide, Radicicol, Atorvastatin, Salionomycin, Temozolomide, (DARAST) inhibits the expression of FABP4, increases the expression of a number of tumor suppressor genes, and stifles the metastatic potential and the progression of ovarian cancers, via up-regulation of its target gene, 16/September/2018, 11.18 pm

Introduction: What they say: A study from the Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, 77030, […]

September 16, 2018

Published by admin_auro at September 16, 2018

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Combinatorial therapy for human cancers: A pharmaceutical mixture encompassing Radicicol, 5′-Aza-2′-deoxycytidine (5-Aza-dC), Andrographlide (ANDRO), Metformin, Berberine, Salinomycin, Fluoxetine, Curcumin, Calcitriol, Pravastatin (RAAMBSFCCR) inhibits the expression of KAT6A and KAT6B, increases the expression of INK4a/ARF and other genes, promotes senescence, prevents cancer recurrence, and prolongs survival, via up-regulation of its target gene, 16/September/2018, 10.55 pm

Introduction: What they say: A study from the Medicinal Chemistry Theme, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia; The Walter and Eliza Hall […]

September 16, 2018

Published by admin_auro at September 16, 2018

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A Probiotic way to lengthen lifespan: Probiotic Lactobacillus casei Zhang may increase insulin sensitivity, slow down cardiac aging, and increase lifespan, via up-regulation of BubR1 and others genes, 16/September/2018, 10.08 pm

What they say: Introduction: A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston, USA; […]

September 16, 2018

Published by admin_auro at September 16, 2018

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Awakening the sleeping/cancer-protecting angels in mutant p53-expressing human tumors: Andrographolide, isolated from Andrographis paniculata, increases the expression of tumor suppressors genes, such as CCM3/KRIT1, TIMP3, p53, p53, TAp63, TAp73, INK4a/ARF, and others, induces regression of p53-mutated human tumors, via down-regulation of its target gene, 16/September/2018, 9.53 pm

From Significance of the study to Public health relevance: Given that: (1) cancer suppressor p53 is mutated in more than 50% of human cancers of different […]