Ideas

September 14, 2018

Published by admin_auro at September 14, 2018

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Ideas
Pain

Probiotics-based induction of the PD-1 pathway for Pain therapy: Probiotics increase the expression of PD-L1, attenuate acute and chronic pain, and suppress mechanical and thermal hypersensitivity and inhibit nociceptive neuron excitability, via up-regulation of its target gene, 14/September/2018, 10.38 pm

Introduction: What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for […]

September 14, 2018

Published by admin_auro at September 14, 2018

Categories

Ideas

Awakening the sleeping/cancer-protecting angels in mutant p53-expressing human tumors: Mibolerone (Trade name: Cheque drops and Matenon), an anabolic-androgenic steroid, increases the expression of tumor suppressors genes, such as PDCD4, CADM1, p53, p53, TAp63, TAp73, INK4a/ARF, and others, induces regression of p53-mutated human tumors, via down-regulation of its target gene, 14/September/2018, 10.29 pm

From Significance of the study to Public health relevance: Given that: (1) cancer suppressor p53 is mutated in more than 50% of human cancers of different […]

September 14, 2018

Published by admin_auro at September 14, 2018

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Awakening the sleeping/cancer-protecting angels in mutant p53-expressing human tumors: Pioglitazone (trade name: Actos), an anti-diabetic drug, increases the expression of tumor suppressors genes, such as VHL, ANP32A, p53, p53, TAp63, TAp73, INK4a/ARF, and others, induces regression of p53-mutated human tumors, via down-regulation of its target gene, 14/September/2018, 10.24 pm

From Significance of the study to Public health relevance: Given that: (1) cancer suppressor p53 is mutated in more than 50% of human cancers of different […]

September 14, 2018

Published by admin_auro at September 14, 2018

Categories

Ideas
Pain

Induction of the PD-1 pathway for Pain therapy: Thiopental (brand name: Pentothal), a general anesthetic, increases the expression of PD-L1, attenuates acute and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 14/September/2018, 8.27 pm

Introduction:What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain […]