Ideas

August 22, 2018
Published by admin_auro at August 22, 2018
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The female steroid hormone functions as a longevity promoter: 17α-Estradiol (trade name: Avicis, Avixis, Ell-Cranell Alpha, and Pantostin), the c-17 epimer of Estradiol,  may  increase insulin sensitivity, slow down cardiac aging, and increase lifespan, via up-regulation of BubR1 and others genes, 22/August/2018, 6.31 am

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston, USA; […]
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August 22, 2018
Published by admin_auro at August 22, 2018
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Consuming olive oil may prolong your lifespan and healthspan: Oleic acid, one of the components of Olive oil, inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian lifespan, via upregulation of its target gene, 22/August/2017, 6.27 am

What they say:  A study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal […]
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August 20, 2018
Published by admin_auro at August 20, 2018
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Awakening the sleeping/cancer-protecting angels in mutant p53-expressing human tumors: PCGF2/Mel-18 increases the expression of tumor suppressors genes, such as  RECK, CADM1, p53, TAp63, TAp73, INK4a/ARF, and others, induces regression of p53-mutated human tumors, via down-regulation of its target gene, 20/August/2018, 7.32 pm

From Significance of the study to Public health relevance:  Given that: (1) cancer suppressor p53 is mutated in more than 50% of human cancers of different […]
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August 20, 2018
Published by admin_auro at August 20, 2018
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Molecular therapy for Myocardial infarction: Nucleolin, a nucleolar phosphoprotein that plays a role in the maturation of ribosomes,  inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction, via up-regulation of PNUTS, 20/August/2018, 7.21 pm

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published, in the 7 March  2013 issue of the […]
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