Ideas – Page 261

August 19, 2018

Published by admin_auro at August 19, 2018

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Estradiol functions as a longevity promoter: Estradiol, a female steroid hormone, inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian lifespan, via upregulation of its target gene, 19/August/2017, 11.23 pm

What they say: A study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal […]

August 18, 2018

Published by admin_auro at August 18, 2018

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Revealing the unrevealed function of the reproductive hormone Relaxin in the heart: Relaxin, a protein hormone that facilitates labor and relaxes the uterine musculature, inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction, via up-regulation of PNUTS, 19/August/2018, 12.35 am

What they say: A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published, in the 7 March 2013 issue of the […]

August 18, 2018

Published by admin_auro at August 18, 2018

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Awakening the sleeping/cancer-protecting angels in mutant p53-expressing human tumors: Emodin, isolated from Rhubarb and others, increases the expression of tumor suppressors genes, such as Smad7, p12DOC1/CDK2AP1, TA-p73, TAp63, p53, and others, induces regression of p53-mutated human tumors, via down-regulation of its target gene, 19/August/2018, 12.13 am

From Significance of the study to Public health relevance: Given that: (1) cancer suppressor p53 is mutated in more than 50% of human cancers of different […]

August 18, 2018

Published by admin_auro at August 18, 2018

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Reproductive hormone aids in the treatment of blood sugar disease: Relaxin-based therapy for DM: Relaxin, a reproductive hormone, increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state, via up-regulation of its target gene Lin28, 19/August/2018, 12.07 am

Introduction: What they say: A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows that “The Lin28/let-7 axis […]