Ideas

August 4, 2018

Published by admin_auro at August 4, 2018

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Unknown function of the known reproductive hormone Progesterone (P4): Progesterone (P4), an endogenous steroid hormone, may aid in the treatment of TIIDM and obesity-associated metabolic deficits: Progesterone (P4) activates an MC4R-dependent anorexigenic pathway, suppresses appetite and weight gain, increases insulin secretion, improves glucose tolerance, promotes glucose homeostasis, improves obesity-associated metabolic deficits and prevents progression to TIIDM, via down-regulation of its target gene, 4/August/2018, 10.53 am

Introduction: What they say A study from the Department of Physiology-Cellular Biophysics, College of Physicians and Surgeons, Columbia University, New York, New York, USA shows that “MC4R-dependent […]

August 4, 2018

Published by admin_auro at August 4, 2018

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Revealing the unrevealed function of the reproductive hormone Follicle-stimulating hormone (FSH) in the heart: FSH, a gonadotropin, and glycoprotein polypeptide hormone, inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction, via up-regulation of PNUTS, 4/August/2018, 9.50 am

What they say: A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published, in the 7 March 2013 issue of the […]

August 3, 2018

Published by admin_auro at August 3, 2018

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Awakening the sleeping/cancer-protecting angels in mutant p53-expressing human tumors: Emodin, isolated from Rhubarb and others, increases the expression of tumor suppressors genes, such as ANP32A, VHL, TA-p73, TAp63, p53, and others, induces regression of p53-mutated human tumors, via down-regulation of its target gene, 3/August/2018, 1.30 pm

From Significance of the study to Public health relevance: Given that: (1) cancer suppressor p53 is mutated in more than 50% of human cancers of different […]

August 3, 2018

Published by admin_auro at August 3, 2018

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Optimal levels of a reproductive hormone FSH(Follicle stimulating hormone) may keep cardiac diseases at bay: FSH-based cardiac rejuvenation therapy: FSH, a gonadotrophin and polypeptide hormone, suppresses tumor suppressor INK4a/p16 expression and inhibits dilated cardiomyopathy, via upregulation of its target gene, 3/August/2018, 1.25 pm

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Optimal levels of a reproductive hormone FSH(Follicle stimulating hormone) may keep cardiac diseases at bay: […]