Ideas – Page 273

August 1, 2018

Published by admin_auro at August 1, 2018

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Ideas
NAFLD

Vaccine for lowering cholesterol, and triglycerides levels: Repurposing the CTB-UE vaccine into a cholesterol-lowering vaccine that inhibits Non-alcoholic fatty liver disease (NAFLD): CTB-UE vaccine, which protects against H.Pylori infection, decreases the levels of HMGCR, triglycerides, free cholesterol, and total cholesterol and prevents the progression of Non-alcoholic fatty liver disease (NAFLD, via down regulation of its target gene, 1/August/2018, 3.16 pm

Significance of the study: Given that: (1) 15-30% of Western populations suffer from Non-alcoholic fatty liver disease (NAFLD), while 6-25% of Asian populations suffer from it; (2) 75 to […]

August 1, 2018

Published by admin_auro at August 1, 2018

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Bacillus Calmette Guerin (BCG)/tuberculosis (TB) vaccine aids in the treatment of Deafness: BCG/TB vaccine increases the expression of ATG5 (Autophagy-related 5), prevents aggregation of proteins in inclusion bodies, inhibits hair cell degeneration, improves hearing loss via upregulation of its target genes, 1/August/2018, 2.10 pm

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Bacillus Calmette Guerin (BCG)/tuberculosis (TB) aids in the treatment of Deafness: BCG/TB vaccine increases the expression […]

August 1, 2018

Published by admin_auro at August 1, 2018

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Reproductive hormone aids in the treatment of blood sugar disease: FSH (Follicle stimulating hormone)-based therapy for DM: FSH increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state, via up-regulation of its target gene Lin28, 1/August/2018, 10.59 am

Introduction: What they say: A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows that “The Lin28/let-7 axis […]

July 30, 2018

Published by admin_auro at July 30, 2018

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Awakening the sleeping/cancer-protecting angels in mutant p53-expressing human tumors: Emodin, isolated from Rhubarb and others, increases the expression of tumor suppressors genes, such as Foxo11, Sprouty-1/2, TA-p73, TAp63, p53, and others, induces regression of p53-mutated human tumors, via down-regulation of its target gene, 31/July/2018, 12.53 am

From Significance of the study to Public health relevance: Given that: (1) cancer suppressor p53 is mutated in more than 50% of human cancers of different […]