Ideas

August 3, 2018

Published by admin_auro at August 3, 2018

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Unknown function of a known reproductive hormone: FSH (Follicle-stimulating hormone) may find its utility in cardiac regenerative therapy: FSH, a gonadotropin and glycoprotein polypeptide hormone, increases the expression of ERBB2/Her2 and promotes dedifferentiation of cardiomyocytes, via down-regulation of its target gene, 3/August/2018, 1.04 pm

Introduction: What they say A recent study from the Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel shows that “ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation.” This study was […]

August 1, 2018

Published by admin_auro at August 1, 2018

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Deoxy sugar-based anti-infective Therapy: D Rhamnose β-hederin (DRβ-H), isolated from Clematis ganpiniana, inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1, respiratory syncytial, Sindbis, and SFV viruses by increasing the Levels of the antiviral Proteins IFITM3, & Interferon-stimulated gene 15, 1/August/2018, 9.54 pm

Introduction: What they say: A study from the Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard Medical School, Charlestown, MA 02129, USA […]

August 1, 2018

Published by admin_auro at August 1, 2018

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Repurposing the H.Pylori vaccine CTB-UE into an anti-diabetic vaccine: CTB-UE vaccine-based therapy for body weight control, energy homeostasis and TIIDM:CTB-UE vaccine, protects against infections caused by H.Pylori, inhibits DNA methyltransferase 3a (Dnmt3a) expression, increases FGF21 expression, augments insulin sensitivity, increases glucose tolerance, and protects from diet-induced obesity and TIIDM, via up-regulation of its target gene, 1/August/2018, 3.34 pm

Introduction: What they say A study from Nutritional Sciences and Toxicology Department, University of California, Berkeley, Berkeley, United States shows that “Dnmt3a is an epigenetic mediator […]

August 1, 2018

Published by admin_auro at August 1, 2018

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Awakening the sleeping/cancer-protecting angels in mutant p53-expressing human tumors: Emodin, isolated from Rhubarb and others, increases the expression of tumor suppressors genes, such as BigH3, TIPE2, TA-p73, TAp63, p53, and others, induces regression of p53-mutated human tumors, via down-regulation of its target gene, 1/August/2018, 3.21 pm

From Significance of the study to Public health relevance: Given that: (1) cancer suppressor p53 is mutated in more than 50% of human cancers of different […]