Ideas

Molecular therapy for Non-alcoholic fatty liver disease (NAFLD): Triiodothyronine, a thyroid hormone (T3),  promotes degradation of HMGCR, decreases the levels of triglycerides, free cholesterol, and total cholesterol and prevents the progression of Non-alcoholic fatty liver disease (NAFLD via down regulation of its target gene, 30/January/2017, 11.41 pm
Molecular therapy for Non-alcoholic fatty liver disease (NAFLD): Triiodothyronine, a thyroid hormone (T3),  promotes degradation of HMGCR, decreases the levels of triglycerides, free cholesterol, and total cholesterol and prevents the progression of Non-alcoholic fatty liver disease (NAFLD via down regulation of its target gene, 30/January/2017, 11.41 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Significance of the study: Given that: (1)  15-30% of Western populations suffer from Non-alcoholic fatty liver disease (NAFLD), while 6-25% of Asian populations suffer from it; (2) 75 to 100 million people in…

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Molecular therapy for anxiety and depression: Sertraline (Brand name: Zoloft, Lustral) decreases PHF8 levels, increases the expression of serotonin receptors Htr1a and Htr2a, and promotes resistance to stress-induced -anxiety and -depression via down regulation of its target gene, 30/January/2018, 11.33 pm
Molecular therapy for anxiety and depression: Sertraline (Brand name: Zoloft, Lustral) decreases PHF8 levels, increases the expression of serotonin receptors Htr1a and Htr2a, and promotes resistance to stress-induced -anxiety and -depression via down regulation of its target gene, 30/January/2018, 11.33 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A study from Department of Molecular Biology, Cancer Center and Center for Regenerative Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA; Department of Stem Cell and…

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Lifespan extension therapy: Pantoprazole (Brand name: Protonix), a drug used in the treatment of stomach ulcers, prolongs mammalian life span via down regulation of angiotensin II type I receptor (AT1R), 30/January/2017, 11.25 pm
Lifespan extension therapy: Pantoprazole (Brand name: Protonix), a drug used in the treatment of stomach ulcers, prolongs mammalian life span via down regulation of angiotensin II type I receptor (AT1R), 30/January/2017, 11.25 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Significance of the study: It has been shown earlier that antagonizing angiotensin II type I receptor (AT1R) expression may prolong mammalian life span. Further, it has been shown that disruption of AT1R (AGTR1)…

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Anti-infective Therapy:  A pharmaceutical mixture encompassing Chlorpromazine  and aspirin inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1,  respiratory syncytial,  Sindbis, and SFV viruses by increasing the Levels of the Antiviral Proteins IFITM3, & Interferon-stimulated gene 15, 30/January/2018,  11.17 pm
Anti-infective Therapy:  A pharmaceutical mixture encompassing Chlorpromazine  and aspirin inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1,  respiratory syncytial,  Sindbis, and SFV viruses by increasing the Levels of the Antiviral Proteins IFITM3, & Interferon-stimulated gene 15, 30/January/2018,  11.17 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A study from the Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard Medical School, Charlestown, MA 02129, USA shows that “The IFITM proteins…

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Antiviral therapy for HIV virus: 9-Aminoacridine increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production via up regulation of its target gene, 30/March/2018, 11.06 pm
Antiviral therapy for HIV virus: 9-Aminoacridine increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production via up regulation of its target gene, 30/March/2018, 11.06 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Department of Biochemistry and Molecular Biophysics and Department of Microbiology and Immunology, Howard Hughes Medical Institute, Columbia University, New York, NY 10032,…

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Molecular therapy for body weight control, energy homeostasis and TIIDM: Pantoprazole (brand name: Protonix), a drug used in the treatment of stomach and duodenal ulcers,  increases REV-ERB and its down stream target genes, inhibits lipid accumulation, improves dyslipidemia and insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM via up regulation of its target gene, 29/January/2018, 11.18 pm
Molecular therapy for body weight control, energy homeostasis and TIIDM: Pantoprazole (brand name: Protonix), a drug used in the treatment of stomach and duodenal ulcers,  increases REV-ERB and its down stream target genes, inhibits lipid accumulation, improves dyslipidemia and insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM via up regulation of its target gene, 29/January/2018, 11.18 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Department of Molecular Therapeutics, The Scripps Research Institute, Jupiter, Florida 33458, USA shows that “Regulation of circadian behaviour and metabolism by synthetic…

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