Ideas

Ribonucleic acid-based therapy protects against and promotes functional recovery after Myocardial Infarction:  LncRNA Mirt2 inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction, via up-regulation of its target gene, 6/July/2019, 10.41 pm
Ribonucleic acid-based therapy protects against and promotes functional recovery after Myocardial Infarction:  LncRNA Mirt2 inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction, via up-regulation of its target gene, 6/July/2019, 10.41 pm 960 720 Dr Boomi's Genom-2-Discovery Center

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published, in the 7 March  2013 issue of of the journal Nature,  by Prof Dimmler,…

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Little RNA can save your heart from failing: Ribonucleic acid-based therapy for cardiomyocyte proliferation and heart regeneration: LncRNA Mirt2 (Long non-coding RNA myocardial infarction associated transcript 2) decreases tumor suppressor MiR-128 and cyclin-dependent kinase inhibitor p27 expression, increases SUZ12 expression, increases Cyclin E and CDK2 expression, promotes proliferation/re-entry of postnatal/adult cardiomyocytes, attenuates fibrosis, ameliorates cardiac dysfunction, and promotes heart repair in response to myocardial infarction, via up-regulation of its target gene, 6/July/2019, 10.25 pm
Little RNA can save your heart from failing: Ribonucleic acid-based therapy for cardiomyocyte proliferation and heart regeneration: LncRNA Mirt2 (Long non-coding RNA myocardial infarction associated transcript 2) decreases tumor suppressor MiR-128 and cyclin-dependent kinase inhibitor p27 expression, increases SUZ12 expression, increases Cyclin E and CDK2 expression, promotes proliferation/re-entry of postnatal/adult cardiomyocytes, attenuates fibrosis, ameliorates cardiac dysfunction, and promotes heart repair in response to myocardial infarction, via up-regulation of its target gene, 6/July/2019, 10.25 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A recent study from Department of Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, 45267, USA; Key Laboratory of Molecular Target and…

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Curing autoimmune diabetes  (TIDM) with HDAC (Histone deacetylase) inhibitors: Givinostat/Gavinostat-based therapy for autoimmune diabetes:Givinostat/Gavinostat, a histone deacetylase inhibitor used to treat systemic juvenile idiopathic arthritis,polycythaemia vera., Duchenne muscular dystrophy and others, increases PD-L1 expression, increases Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up-regulation of its target gene, 5/July/2019, 11.19 pm
Curing autoimmune diabetes  (TIDM) with HDAC (Histone deacetylase) inhibitors: Givinostat/Gavinostat-based therapy for autoimmune diabetes:Givinostat/Gavinostat, a histone deacetylase inhibitor used to treat systemic juvenile idiopathic arthritis,polycythaemia vera., Duchenne muscular dystrophy and others, increases PD-L1 expression, increases Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up-regulation of its target gene, 5/July/2019, 11.19 pm 1280 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the International Center for T1D, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, “L. Sacco” Department of Biomedical and Clinical Sciences, University of…

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The tiny probiotic may increase the lifespan of mighty humans: Probiotic-based therapy for aging-associated diseases and Lifespan extension: Probiotic Lactobacillus plantarum AR501 inhibits the interaction of DBC1 with PARP1, increases the PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer, and aging, via down-regulation of its target gene, 5/July/2019, 10.34 pm
The tiny probiotic may increase the lifespan of mighty humans: Probiotic-based therapy for aging-associated diseases and Lifespan extension: Probiotic Lactobacillus plantarum AR501 inhibits the interaction of DBC1 with PARP1, increases the PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer, and aging, via down-regulation of its target gene, 5/July/2019, 10.34 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from Department of Genetics, Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA, USA; and Department of Pharmacology, School…

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Where the peel is more valuable than the fruit (pulp): Citrus peel is enriched with longevity-promoting compounds than pulp: Citrus peel-based Lifespan extension therapy:  A pharmaceutical mixture encompassing Hesperidin, Tangeretin & Nobiletin (HTN), derived from citrus peel,  inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian lifespan by regulating the expression of its target genes, 5/July/2019, 10.17 pm
Where the peel is more valuable than the fruit (pulp): Citrus peel is enriched with longevity-promoting compounds than pulp: Citrus peel-based Lifespan extension therapy:  A pharmaceutical mixture encompassing Hesperidin, Tangeretin & Nobiletin (HTN), derived from citrus peel,  inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian lifespan by regulating the expression of its target genes, 5/July/2019, 10.17 pm 1280 720 Dr Boomi's Genom-2-Discovery Center

What they say: A study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal protein S6 kinase 1…

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Curing autoimmune diabetes  (TIDM) with interleukin 1 receptor antagonists:Anakinra-based therapy for autoimmune diabetes: Anakinra (brand name: Kineret and others),  an interleukin 1 receptor antagonist used in the treatment of rheumatoid arthritis, increases PD-L1 expression, increases Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up-regulation of its target gene, 4/July/2019, 11.03 pm
Curing autoimmune diabetes  (TIDM) with interleukin 1 receptor antagonists:Anakinra-based therapy for autoimmune diabetes: Anakinra (brand name: Kineret and others),  an interleukin 1 receptor antagonist used in the treatment of rheumatoid arthritis, increases PD-L1 expression, increases Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up-regulation of its target gene, 4/July/2019, 11.03 pm 1280 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the International Center for T1D, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, “L. Sacco” Department of Biomedical and Clinical Sciences, University of…

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