Rotavirus Vaccine-based curative therapy for autoimmune (Type I) diabetes (TIDM): Rotavirus vaccine promotes the expression of PD-L1, attenuates the expression of tumor suppressor TXNIP, augments Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up regulation of its target gene, 4/July/2019, 8.17 pm
Introduction: What they say A study from the International Center for T1D, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, “L. Sacco” Department of Biomedical and Clinical Sciences, University of Milan, Milan 20157, Italy; and Nephrology Division, Boston Children’s Hospital, Harvard Medical School, Boston, MA 02115, USA shows that “PD-L1 genetic overexpression or pharmacological restoration in hematopoietic stem and progenitor […]
Probiotic-based therapy for aging-associated diseases and Lifespan extension: Probiotic Lactobacillus Fermentum DR9 ( (LF-DR9) inhibits the interaction of DBC1 with PARP1, increases the PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer, and aging, via down-regulation of its target gene, 4/July/2019, 8.17 am
Introduction: What they say A study from Department of Genetics, Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA, USA; and Department of Pharmacology, School of Medical Sciences, The University of New South Wales, Sydney, New South Wales 2052, Australia shows that “A conserved NAD+ binding pocket that regulates protein-protein […]
Ribonucleic acid-based therapy for aging-associated diseases and Lifespan extension: LncRNA PCAT5 inhibits the interaction of DBC1 with PARP1, increases the PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer, and aging, via down-regulation of its target gene, 2/July/2019, 11.58 pm
Introduction: What they say A study from Department of Genetics, Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA, USA; and Department of Pharmacology, School of Medical Sciences, The University of New South Wales, Sydney, New South Wales 2052, Australia shows that “A conserved NAD+ binding pocket that regulates protein-protein […]
Probiotic-based curative therapy for autoimmune (Type I) diabetes (TIDM): Lacto-RAC/STBB [(Lactobacillus-Reuteri (LR)/Acidophilus (LA)/Casei (LC), Streptococcus Thermophilus (ST), & Bifidobacterium Bifidum (BB))] promotes the expression of PD-L1, attenuates the expression of tumor suppressor TXNIP, augments Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up regulation of its target gene, 2/July/2019, 10.17 pm
Introduction: What they say A study from the International Center for T1D, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, “L. Sacco” Department of Biomedical and Clinical Sciences, University of Milan, Milan 20157, Italy; and Nephrology Division, Boston Children’s Hospital, Harvard Medical School, Boston, MA 02115, USA shows that “PD-L1 genetic overexpression or pharmacological restoration in hematopoietic stem and progenitor […]
Solving a long standing allopathic conundrum as to how ayurvedic medicine Goggul attenuates cognitive dysfunction and prevents neurodegeneration: Mechanistic insights into how Z-Guggulsterone, derived from Goggul, attenuates cognitive dysfunction and neurodegeneration: Z-Guggulsterone, isolated from Commiphora wightii (commonly known as Goggul) resins and oil, decreases vascular cell adhesion molecule 1 (VCAM 1), inhibits microglia activity, increases hippocampal neural precursor activity, ameliorates cognition, & attenuates age-related neurodegeneration, through up regulation of its target genes, 1/July/2019, 11.58 pm
Introduction: What they say A study from the Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA, VA Palo Alto Health Care System, Palo Alto, CA, USA, Palo Alto Veterans Institute for Research, Palo Alto, CA, USA, Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA, USA shows that “Aged blood […]
Live longer by consuming coconut: Lauric acid or dodecanoic acid-based Lifespan extension therapy: Lauric acid or dodecanoic acid, derived from coconut oil, inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian lifespan by regulating the expression of its target genes, 1/July/2019, 10.41 pm
What they say: A study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal protein S6 kinase 1 signaling regulates mammalian life span.” This study was published, in the 2 October 2009 issue of the Journal “Science” (I.F: 37.205 ), by Prof. Dominic J. Withers, Dr. Selman C, […]