Ideas

Molecular therapy for Diabetic retinopathy: A pharmaceutical mixture encompassing Efonidipine, Epicatechin and Marine (EPEM) inhibits Soluble epoxide hydrolase (sEH) expression, decreases toxic 19,20-dihydroxydocosapentaenoic acid levels, inhibits pericyte loss, vascular permeability, and inflammation of the eye and progression of diabetic retinopathy, via down regulation of its target gene, 7/January/2018, 11.40 pm
Molecular therapy for Diabetic retinopathy: A pharmaceutical mixture encompassing Efonidipine, Epicatechin and Marine (EPEM) inhibits Soluble epoxide hydrolase (sEH) expression, decreases toxic 19,20-dihydroxydocosapentaenoic acid levels, inhibits pericyte loss, vascular permeability, and inflammation of the eye and progression of diabetic retinopathy, via down regulation of its target gene, 7/January/2018, 11.40 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe University, Frankfurt am Main, Germany; and German Centre for Cardiovascular Research (DZHK) partner…

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Lifespan extension therapy:  Tomatidine, a glycoalkaloid isolated from unripe tomato, increases life span via up-regulation of its target gene BubR1, 7/January/2017, 11.28 pm
Lifespan extension therapy:  Tomatidine, a glycoalkaloid isolated from unripe tomato, increases life span via up-regulation of its target gene BubR1, 7/January/2017, 11.28 pm 960 720 Dr Boomi's Genom-2-Discovery Center

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and Department of Pharmacology, School…

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Molecular therapy for Metastatic cancers: Torasemide, an anti-hypertensive drug, increases the expression of tumor suppressors TPM1 and TAp63, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 7/January/2017, 11.17 pm
Molecular therapy for Metastatic cancers: Torasemide, an anti-hypertensive drug, increases the expression of tumor suppressors TPM1 and TAp63, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 7/January/2017, 11.17 pm 960 720 Dr Boomi's Genom-2-Discovery Center

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more than half of them…

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Anti-infective Therapy: Tomatidine, a glycoalkaloid isolated from unripe tomato, inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1,  respiratory syncytial,  Sindbis, and SFV viruses by increasing the Levels of the Antiviral Proteins IFITM3, & Interferon-stimulated gene 15, 7/January/2017,  11.04 pm
Anti-infective Therapy: Tomatidine, a glycoalkaloid isolated from unripe tomato, inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1,  respiratory syncytial,  Sindbis, and SFV viruses by increasing the Levels of the Antiviral Proteins IFITM3, & Interferon-stimulated gene 15, 7/January/2017,  11.04 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A study from the Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard Medical School, Charlestown, MA 02129, USA shows that “The IFITM proteins…

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Molecular therapy for Diabetic retinopathy: A pharmaceutical mixture encompassing Fimasartan, Epicatechin and Marine (FSEM) inhibits Soluble epoxide hydrolase (sEH) expression, decreases toxic 19,20-dihydroxydocosapentaenoic acid levels, inhibits pericyte loss, vascular permeability, and inflammation of the eye and progression of diabetic retinopathy, via down regulation of its target gene, 7/January/2018, 10.55 pm
Molecular therapy for Diabetic retinopathy: A pharmaceutical mixture encompassing Fimasartan, Epicatechin and Marine (FSEM) inhibits Soluble epoxide hydrolase (sEH) expression, decreases toxic 19,20-dihydroxydocosapentaenoic acid levels, inhibits pericyte loss, vascular permeability, and inflammation of the eye and progression of diabetic retinopathy, via down regulation of its target gene, 7/January/2018, 10.55 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe University, Frankfurt am Main, Germany; and German Centre for Cardiovascular Research (DZHK) partner…

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Antiviral therapy against Neuroinvasive West Nile virus: Nimodipine, an anti-hypertensive agent, increases the expression of RIPK3, promotes chemokines production, inhibits neuroinflammation, and restricts neuroinvasive West Nile virus production and pathogenesis in neurons via up regulation of its target gene, 7/January/2017, 10.38 pm
Antiviral therapy against Neuroinvasive West Nile virus: Nimodipine, an anti-hypertensive agent, increases the expression of RIPK3, promotes chemokines production, inhibits neuroinflammation, and restricts neuroinvasive West Nile virus production and pathogenesis in neurons via up regulation of its target gene, 7/January/2017, 10.38 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Department of Immunology, University of Washington, Seattle, WA 98109, USA; Center for Innate Immunity and Immune Disease, University of Washington, Seattle, WA 98109,…

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