Ideas

Vitamin-based Lifespan extension therapy: Pyridoxamine (PM), a form of Vitamin B (6),  increases life span via up-regulation of its target gene BubR1, 17/December/2017, 11.51 pm
Vitamin-based Lifespan extension therapy: Pyridoxamine (PM), a form of Vitamin B (6),  increases life span via up-regulation of its target gene BubR1, 17/December/2017, 11.51 pm 960 720 Dr Boomi's Genom-2-Discovery Center

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and Department of Pharmacology, School…

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Natural product therapy for pulmonary arterial hypertension: Glycyrrhetinic acid, isolated from Licorice, inhibits the development of pulmonary arterial hypertension via down regulation of its target gene Notch3, 17/December/2017, 11.42 pm
Natural product therapy for pulmonary arterial hypertension: Glycyrrhetinic acid, isolated from Licorice, inhibits the development of pulmonary arterial hypertension via down regulation of its target gene Notch3, 17/December/2017, 11.42 pm 960 720 Dr Boomi's Genom-2-Discovery Center

What they say:  A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published, in the 15 November  2009 issue of the journal “Nature Medicine”[the number 1 journal in…

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Molecular therapy for Cardiomyopathy: A pharmaceutical mixture (PMSFN) encompassing  Pyridoxamin (PM) and Sulphoraphane (SFN) decreases the expression of Sox6, restores the balance between slow- and fast-twitch myofiber proteins and alleviates Cardiomyopathy via up regulation of its target gene, 17/December/2017,  11.03 pm
Molecular therapy for Cardiomyopathy: A pharmaceutical mixture (PMSFN) encompassing  Pyridoxamin (PM) and Sulphoraphane (SFN) decreases the expression of Sox6, restores the balance between slow- and fast-twitch myofiber proteins and alleviates Cardiomyopathy via up regulation of its target gene, 17/December/2017,  11.03 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say   A study from the Department of Cardiology, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, USA; and Harvard Stem Cell Institute, Harvard University, Cambridge, Massachusetts, USA shows that “Trbp regulates heart function through microRNA-mediated Sox6 repression.” This…

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Amino acid-based therapy for ageing-associated diseases and Lifespan extension: D-Serine increases NMN/NAD levels, decreases interaction of DBC1 with PARP1, increases PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer and aging via down regulation of its target gene, 17/December/2017, 10.52 pm
Amino acid-based therapy for ageing-associated diseases and Lifespan extension: D-Serine increases NMN/NAD levels, decreases interaction of DBC1 with PARP1, increases PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer and aging via down regulation of its target gene, 17/December/2017, 10.52 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from Department of Genetics, Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA, USA; and Department of Pharmacology, School…

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Natural product-derived combinatorial therapy for Myocardial Infarction: A pharmaceutical mixture encompassing Pyridoxamine (PM) and Sulforaphane (SFN) inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via up regulation of PNUTS,  16/December/2017, 11.49 pm
Natural product-derived combinatorial therapy for Myocardial Infarction: A pharmaceutical mixture encompassing Pyridoxamine (PM) and Sulforaphane (SFN) inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via up regulation of PNUTS,  16/December/2017, 11.49 pm 960 720 Dr Boomi's Genom-2-Discovery Center

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published, in the 7 March  2013 issue of Nature,  by Prof Dimmler, Boon, and others. What we…

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Natural product-based therapy for Diabetic retinopathy: Notoginsenoside R1, isolated from Panax Notoginseng, inhibits Soluble epoxide hydrolase (sEH) expression, decreases toxic 19,20-dihydroxydocosapentaenoic acid levels, inhibits pericyte loss, vascular permeability, and inflammation of the eye and progression of diabetic retinopathy, via down regulation of its target gene, 16/December/2017, 11.38 pm
Natural product-based therapy for Diabetic retinopathy: Notoginsenoside R1, isolated from Panax Notoginseng, inhibits Soluble epoxide hydrolase (sEH) expression, decreases toxic 19,20-dihydroxydocosapentaenoic acid levels, inhibits pericyte loss, vascular permeability, and inflammation of the eye and progression of diabetic retinopathy, via down regulation of its target gene, 16/December/2017, 11.38 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe University, Frankfurt am Main, Germany; and German Centre for Cardiovascular Research (DZHK) partner…

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