Ideas

Combinatorial Antiviral Therapy (CAT): Metformin, the widely used drug in the treatment of TIIDM, inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1,  respiratory syncytical ,  Sindbis, and SFV viruses by increasing the Levels of the Antiviral Proteins IFITM3, & Interferon-stimulated gene 15, 22/December/2017,  12.33 am

Combinatorial Antiviral Therapy (CAT): Metformin, the widely used drug in the treatment of TIIDM, inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1,  respiratory syncytical ,  Sindbis, and SFV viruses by increasing the Levels of the Antiviral Proteins IFITM3, & Interferon-stimulated gene 15, 22/December/2017,  12.33 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say:  A study from the Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard Medical School, Charlestown, MA 02129, USA shows that “The IFITM proteins…

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Molecular therapy for anxiety and depression: Pioglitazone, an anti-hyperglycemic medication, decreases PHF8 levels, increases the expression of serotonin receptors Htr1a and Htr2a, and promotes resistance to stress-induced -anxiety and -depression via down regulation of its target gene, 22/December/2017, 12. 21 am

Molecular therapy for anxiety and depression: Pioglitazone, an anti-hyperglycemic medication, decreases PHF8 levels, increases the expression of serotonin receptors Htr1a and Htr2a, and promotes resistance to stress-induced -anxiety and -depression via down regulation of its target gene, 22/December/2017, 12. 21 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A study from Department of Molecular Biology, Cancer Center and Center for Regenerative Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA; Department of Stem Cell and…

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Natural product-based therapy for Deafness: A therapeutic mix encompassing Rosmarinic acid, Cholecalciferol  and DIM (RACAD) increases the expression of ATG5 (Autophagy-related 5), prevents aggregation of proteins in inclusion bodies, inhibits hair cell degeneration,  and improves hearing loss via up regulation of its target genes, 22/December/2017, 12.07 am

Natural product-based therapy for Deafness: A therapeutic mix encompassing Rosmarinic acid, Cholecalciferol  and DIM (RACAD) increases the expression of ATG5 (Autophagy-related 5), prevents aggregation of proteins in inclusion bodies, inhibits hair cell degeneration,  and improves hearing loss via up regulation of its target genes, 22/December/2017, 12.07 am 960 720 Dr Boomi's Genom-2-Discovery Center

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Natural product-based therapy for Deafness: A therapeutic mix encompassing Rosmarinic acid, Cholecalciferol  and DIM (RACAD) increases the expression of ATG5…

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Lifespan extension therapy: Resveratrol, a longevity-promoting compound,  may increase life span via up-regulation of its target gene BubR1, 21/November/2017, 11.54 pm

Lifespan extension therapy: Resveratrol, a longevity-promoting compound,  may increase life span via up-regulation of its target gene BubR1, 21/November/2017, 11.54 pm 960 720 Dr Boomi's Genom-2-Discovery Center

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and Department of Pharmacology, School…

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Molecular therapy for inflammation and arthritis: Dextromethorphan (Brand name: Robitussin, Delsym, DM, DexAlone, Duract), a cough suppressant,  increases IL-9 levels, augments proliferation of ILC2s (type 2 innate lymphoid cells) and regulatory T (Treg) cells, promotes resolution of inflammation, attenuates cartilage destruction, decreases bone loss, and inhibits pathological features associated with arthritis via up regualtion of its target genes, 21/December/2017, 11.40 pm

Molecular therapy for inflammation and arthritis: Dextromethorphan (Brand name: Robitussin, Delsym, DM, DexAlone, Duract), a cough suppressant,  increases IL-9 levels, augments proliferation of ILC2s (type 2 innate lymphoid cells) and regulatory T (Treg) cells, promotes resolution of inflammation, attenuates cartilage destruction, decreases bone loss, and inhibits pathological features associated with arthritis via up regualtion of its target genes, 21/December/2017, 11.40 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from Department of Internal Medicine 3-Rheumatology and Immunology, Friedrich Alexander University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany shows that “Resolution of inflammation by…

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Molecular therapy for blood-stage Plasmodium infection: Metformin, the anti-hyperglycemic medication, decreases the expression of CTLA-4, PD-L1 and LAG-3, promotes CD4+ T-cell function, increases secretion of protective antibodies, promotes and clear blood-stage malaria via up regulation of its target gene, 21/December/2017, 6.58 am

Molecular therapy for blood-stage Plasmodium infection: Metformin, the anti-hyperglycemic medication, decreases the expression of CTLA-4, PD-L1 and LAG-3, promotes CD4+ T-cell function, increases secretion of protective antibodies, promotes and clear blood-stage malaria via up regulation of its target gene, 21/December/2017, 6.58 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Department of Microbiology and Immunology, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA shows that “Regulatory T cells impede…

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